MENOPAUSE

This study will follow about 2,700 women aged 45-75 who are going through menopause and have a higher risk of heart disease. Researchers want to see if newer hormone replacement therapies (like creams, gels, or sprays) can lower the chance of heart attacks, strokes, or other hear…

This study tests whether a daily prebiotic drink can improve blood sugar control in 30 postmenopausal women with prediabetes. The drink contains inulin, a fiber that feeds good gut bacteria. Over 4 weeks, researchers will measure changes in fasting glucose and other metabolic mar…

This study tests whether estradiol (estrogen) patches can improve healing and reduce pain after rotator cuff surgery in postmenopausal women. About 58 women aged 50-80 will receive either estradiol or placebo patches for a short time after their operation. The goal is to see if t…

This study looks at whether taking blackcurrant supplements can slow bone loss in women after menopause. The researchers will measure bone density and changes in gut bacteria over 12 months. About 159 women aged 45-70 who are not on hormone therapy will take either blackcurrant c…

This study compares two vaginal treatments—estrogen and DHEA—for common menopause symptoms like dryness, discomfort, and painful sex. About 324 perimenopausal and menopausal women will be randomly assigned to one treatment and complete questionnaires and simple tests. The goal is…

This study tests whether hormone therapy (estrogen with or without progesterone) can safely reduce hot flashes and night sweats in women with HIV. Researchers will also check if it improves sleep, mood, thinking, bone health, and heart health. The trial will enroll 105 women aged…

This study tests whether a gentle, noninvasive electrical brain stimulation (called transcranial electrical stimulation) is tolerable and can help with menopause symptoms like hot flashes, depression, anxiety, memory problems, and muscle issues. About 50 women aged 40-60 going th…

This study tests whether an 8-week mindfulness program can reduce hot flashes and improve sleep in menopausal women. Researchers will randomly assign 90 women to either the mindfulness group or a no-treatment control group. The program includes weekly sessions on breathing, body …

This study looks at whether a 12-week online facial yoga program can help menopausal women aged 45-65 feel less stressed, think more clearly, and lower their cortisol levels. One hundred women will be split into two groups: one does facial yoga twice a week, the other continues u…

This study tests whether a 12-week foot and ankle strengthening program can improve physical function and quality of life in menopausal women. About 70 women aged 45-65 will either do the exercises or continue their usual activities. The goal is to see if targeting the feet and a…

This study looks at whether laughter yoga can help menopausal women feel better, sleep better, and enjoy life more. Eighty women will be split into two groups: one does laughter yoga for 8 sessions, the other does nothing new. Researchers will compare symptoms, sleep, and quality…

This study explores whether coloring mandalas (intricate circular patterns) for 30 minutes once a week over 4 weeks can reduce menopause symptoms, improve sexual quality of life, and boost self-esteem in women aged 40-65 who are experiencing moderate to severe menopause symptoms.…

This study will adapt and test a cognitive behavioral therapy program specifically for women veterans aged 45 and older who are experiencing menopause symptoms. The goal is to improve their daily functioning and quality of life. About 48 participants from the VA Maryland Healthca…

This study tests whether a testosterone gel applied to the skin can safely improve low sexual desire and arousal in women going through or past menopause. About 150 women aged 40-65 with diagnosed low libido will receive either the gel or a placebo for several weeks. The goal is …

This study aims to find better ways to deliver health services to women Veterans, especially those in midlife. Researchers will test two different strategies at 18 VA sites to see which one helps more women get the care they need. The study focuses on improving engagement with pr…

This study looks at how menopause changes the way the body processes escitalopram, a common antidepressant. Researchers will compare drug levels in premenopausal and postmenopausal women aged 40-60 who take the medication for depression or anxiety. The goal is to help doctors per…

This study looks at how menopause and poor sleep affect the heart in women with type 2 diabetes. Researchers will track 381 women aged 48-58 to measure changes in heart function using ultrasound. The goal is to understand these links, not to test a treatment.

This study looks at how menopausal hormone therapy (MHT) affects the heart's ability to pump blood. Researchers will compare heart function in postmenopausal women who use MHT and those who don't. The goal is to understand the role of the nervous system in controlling heart perfo…

This study aims to understand how women aged 45 to 60 experience and think about menopause. Researchers will talk with 24 women who are part of a special group program at a Paris hospital. The goal is to learn about their feelings, challenges, and what helps them, so doctors can …

This study aims to create a national registry of menopausal women in Brazil, aged 35 to 65, to understand how menopause affects their health, quality of life, and access to healthcare. Researchers will look at differences based on region, income, and social factors. The goal is t…

This study aims to find out if removing the fallopian tubes at the time of hysterectomy causes menopause to start earlier. It includes 2,100 women under 55 who had a hysterectomy and were randomly assigned to have their tubes removed or not. Participants will collect a few drops …