Talking therapy could ease menopause mood swings without hormones

NCT ID NCT06462157

Completed Symptom relief Sponsor: University College, London Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a 6-session online group program called Compassionate Mind Training (CMT) can improve wellbeing in women aged 40-60 going through menopause. The therapy aims to reduce self-criticism and shame by building self-compassion. Researchers enrolled 38 women to see if the approach is practical and acceptable, and to measure changes in mood, anxiety, and quality of life. This is a very early feasibility study, not a large-scale effectiveness trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Compassionate Mind Training (CMT) - a psychological therapy delivered in online group sessions
What this could lead to: If it works, this could offer a non-hormonal, drug-free option to help women manage menopause-related emotional difficulties like low mood and self-criticism.
What could go wrong: This is a very small, early feasibility study with only 38 participants and no control group for efficacy. Results may not apply to all women, and the therapy may not produce lasting benefits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENOPAUSE

Contacts and locations

Locations

University College London

London, County, WC1E 6BT, United Kingdom

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