Brain scans reveal why menopause makes some women snappy

NCT ID NCT05388656

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study involved 40 women in early menopause who reported increased irritability. Researchers gave them either estrogen patches or placebo patches to see how their brains reacted to hormone changes. The goal was to understand the brain mechanisms behind mood swings, not to test a treatment. Results may help develop better ways to manage irritability in the future.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Carolina Crossing B, Suite 1

    Chapel Hill, North Carolina, 27517, United States

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