Can a natural supplement boost heart drug benefits in older women?
NCT ID NCT05877235
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 60 postmenopausal women with stable coronary artery disease. Researchers tested whether adding a daily 1000 mg quercetin supplement to standard atorvastatin treatment could affect levels of estrogen and a protein called SIRT1, which are linked to heart health. The goal was to see if this combination might offer extra benefits beyond statins alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
quercetin (a natural antioxidant found in fruits and vegetables) and atorvastatin (a statin drug)
What this could lead to
If it works, this could point toward a way to improve heart health in postmenopausal women by combining a common statin with a natural supplement.
What could go wrong
This is a small, early-stage study (60 participants) that only measured blood markers, not actual heart events. The results may not lead to a new treatment or apply to all women.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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INCOR- Heart Institute
São Paulo, São Paulo, 05403900, Brazil