HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Clinical trials for HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM explained in plain language.
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Can the HPV vaccine protect stem cell transplant patients?
⭐️ VACCINE ⭐️ OngoingThis study tests whether the Gardasil 9 vaccine can help stem cell transplant patients build immunity against HPV. About 48 adults who had a stem cell transplant for blood cancer will receive the vaccine. Researchers will measure antibody levels to see if the vaccine works in the…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE4 • Sponsor: M.D. Anderson Cancer Center • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:35 UTC
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New vaccine aims to shield transplant patients from deadly virus
⭐️ VACCINE ⭐️ OngoingThis study tests a vaccine called Triplex to prevent cytomegalovirus (CMV) infection in adults who have received a stem cell transplant. CMV is usually harmless but can be life-threatening for people with weakened immune systems. The vaccine uses harmless virus pieces to train th…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 07:57 UTC
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New combo therapy aims to boost immune attack on hard-to-treat cancers
Disease control OngoingThis early-phase study tests the safety of the immunotherapy drug atezolizumab given after a patient's own immune cells have been modified and infused back (adoptive cell transfer). It includes 40 adults with advanced blood or solid cancers that no longer respond to standard trea…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Donor T-Cells take on stubborn CMV in transplant patients
Disease control OngoingThis phase 2 trial tests whether immune cells from donors who have been exposed to CMV can treat persistent CMV infections in patients who have had a stem cell transplant. The study includes 49 participants with CMV that hasn't improved with standard antiviral drugs. The cells ar…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Childhood cancer immunotherapy trial pulled before it started
Disease control TerminatedThis study was designed to test two immunotherapy drugs, nivolumab and ipilimumab, in children and young adults with cancers that returned or didn't respond to treatment and had many genetic mutations. The goal was to see if the drug combination was safe and could shrink tumors. …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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New drug combo shows promise for rare genetic cancers
Disease control OngoingThis study tests two drugs, dabrafenib and trametinib, in people with advanced cancers that have a specific genetic change called a BRAF V600 mutation. The goal is to see if these drugs can shrink tumors or stop them from growing. The trial includes 44 participants with various c…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Could goat milk help prevent a deadly transplant side effect?
Disease control OngoingThis early-phase study tests whether drinking milk from genetically engineered goats (which produce a human enzyme found in breast milk) can reduce the risk of graft versus host disease—a serious immune reaction—in blood cancer patients receiving a donor stem cell transplant. Abo…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Targeted pill takes aim at rare cancer mutations
Disease control OngoingThis phase 2 trial is testing the drug osimertinib in 19 patients with advanced cancers (like lymphoma or solid tumors) that have specific EGFR mutations. Osimertinib is a pill that blocks the faulty EGFR protein, which can help stop tumor growth. The study aims to see if the dru…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New drug targets Hard-to-Treat cancers with PTEN mutation
Disease control OngoingThis phase II trial tests a drug called GSK2636771 in 24 patients whose advanced cancers have a PTEN mutation or deletion. The drug blocks a protein (PI3K-beta) that may help these cancer cells grow. Researchers want to see if the drug can shrink tumors or stop them from growing.
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New drug targets Hard-to-Treat cancers with PTEN loss
Disease control OngoingThis phase II trial tests a drug called GSK2636771 in 35 patients whose cancers have lost a protein called PTEN. The drug blocks a growth signal that these cancers may rely on. Researchers hope to see if it can shrink tumors or stop them from growing.
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Cord blood stem cells aim to tame COVID-19 lung crisis
Disease control OngoingThis study tests whether infusions of cord blood stem cells can help people with moderate to critical COVID-19 pneumonia. The trial includes 65 adults with COVID-19-related acute respiratory distress syndrome (ARDS). Researchers will compare stem cell treatment plus standard care…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Can radiation reignite cancer control after immunotherapy fails?
Disease control OngoingThis phase II trial tests whether radiation therapy can help control cancer that has spread or grown after immunotherapy. About 230 patients with metastatic or lymphoid cancers will receive targeted radiation to see if it stabilizes the disease or shrinks tumors. The study also m…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New hope for NRAS-Mutant cancers: targeted drug binimetinib under study
Disease control OngoingThis phase II trial is testing the drug binimetinib in 53 people whose cancers (excluding melanoma) have a specific genetic change called an NRAS mutation. Binimetinib blocks certain proteins that help these cancer cells grow. The study aims to see if the drug can shrink tumors o…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Targeted drug crizotinib tested against rare ALK-driven cancers
Disease control OngoingThis phase 2 trial tests the drug crizotinib in patients with advanced cancers (other than lung cancer) that have a specific genetic change called ALK rearrangement. Crizotinib works by blocking the ALK protein, which may stop cancer cells from growing. The study enrolled only 5 …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Targeted drug trametinib tested on rare BRAF cancers
Disease control OngoingThis phase II trial tests the drug trametinib in 35 patients with advanced cancers that have certain BRAF mutations or fusions. The goal is to see if trametinib can shrink or stop cancer growth by blocking proteins that help cancer cells grow. The study focuses on patients whose …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Targeted drug shows promise for rare HER2-Positive cancers
Disease control OngoingThis study tests a drug called ado-trastuzumab emtansine in people whose cancers have too many HER2 receptors (HER2 amplification), but not breast or stomach cancers. The drug combines an antibody that targets HER2 with a chemotherapy agent to kill cancer cells. Researchers want …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Targeted drug shows promise for rare NF2-Mutated cancers
Disease control OngoingThis phase II trial is testing the drug defactinib in 35 patients whose advanced cancers have a specific genetic change called an NF2 mutation. The drug works by blocking a protein that may help these cancer cells grow. Researchers want to see if defactinib can shrink tumors or s…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New drug targets BRCA cancers in precision medicine trial
Disease control OngoingThis study tests a drug called AZD1775 in people whose advanced cancers have a BRCA1 or BRCA2 gene mutation. The drug blocks a protein (WEE1) that helps cancer cells grow. Researchers want to see if it can shrink tumors or stop them from growing. About 35 adults with various adva…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New drug targets AKT mutation in Hard-to-Treat cancers
Disease control OngoingThis phase 2 trial tests capivasertib (AZD5363) in 35 patients with advanced cancers that have an AKT mutation. The drug blocks a protein that helps cancer cells grow. Researchers want to see if it can shrink tumors or stop them from growing.
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New drug targets genetic weakness in Hard-to-Treat cancers
Disease control OngoingThis phase II trial tests the drug taselisib in 70 patients with advanced cancers (excluding breast cancer) that have a specific genetic change called a PIK3CA mutation. The drug works by blocking a protein that helps cancer cells grow. Researchers want to see if taselisib can sh…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Targeted drug shows promise for rare ROS1 cancers
Disease control OngoingThis study tests a drug called crizotinib in people whose cancer has a specific genetic change called ROS1 translocation. The drug blocks a protein that may help cancer grow. Researchers want to see if it can shrink tumors or stop them from getting worse. Only 4 people took part,…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Promising drug for immunotherapy side effects never tested: trial withdrawn
Disease control TerminatedThis phase II trial aimed to test the drug itacitinib in people with severe side effects from cancer immunotherapy that did not get better with steroids. The goal was to see if itacitinib could calm the overactive immune response causing these side effects. However, the study was…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: Douglas Johnson • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Targeted drug afatinib tested against HER2-Mutated tumors
Disease control OngoingThis phase II trial tests the drug afatinib in 40 people with advanced cancers (like solid tumors or lymphoma) that have a specific genetic change called a HER2 mutation. Afatinib works by blocking the HER2 protein, which may help stop cancer growth. The study aims to see if the …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Targeted drug takes aim at NF1-Mutated cancers
Disease control OngoingThis phase II trial is testing the drug trametinib in 50 people with advanced cancers that have a specific genetic change called an NF1 mutation. Trametinib blocks certain proteins that help cancer cells grow. The goal is to see if the drug can shrink tumors or stop them from get…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Targeted drug trial aims at rare cancer mutations
Disease control OngoingThis phase II trial tests the drug trametinib in people whose advanced cancers have specific genetic changes called GNAQ or GNA11 mutations. The drug works by blocking certain proteins that help cancer cells grow. Researchers want to see if trametinib can shrink these tumors or s…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Targeted drug palbociclib tested against cancers with specific genetic flaw
Disease control OngoingThis phase II trial is testing the drug palbociclib in 40 patients whose advanced cancers have extra copies of the CCND1, 2, or 3 genes. Palbociclib blocks proteins that help cancer cells grow. The goal is to see if the drug can shrink tumors or stop them from growing. The study …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Could a probiotic help stem cell transplant recovery?
Disease control OngoingThis early-phase trial tests whether a probiotic called CBM588 is safe and can improve outcomes in 36 patients who have received a donor stem cell transplant. The probiotic aims to increase healthy gut bacteria and reduce gut-related side effects like diarrhea and colon inflammat…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New transplant recipe may tame Graft-Versus-Host disease in blood cancer patients
Disease control OngoingThis study tests a specific timing of chemotherapy drugs (busulfan and fludarabine) before a donor stem cell transplant, followed by cyclophosphamide after the transplant, to treat high-risk blood cancers like leukemia and lymphoma. The goal is to reduce the chance of the transpl…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New antibody takes aim at Hard-to-Treat blood cancers
Disease control OngoingThis early-stage trial tests a new antibody drug called Hu8F4 in 72 people with advanced blood cancers like leukemia and myelodysplastic syndrome. The goal is to find the safest dose and see if it can slow or stop cancer growth. Researchers will also track how long patients live …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Can exercise and a B3 supplement help cancer survivors fight prediabetes?
Disease control OngoingThis pilot study looks at whether a home exercise program plus a dietary supplement called nicotinamide riboside (similar to vitamin B3) can improve muscle health and insulin resistance in adult survivors of childhood cancer who have prediabetes. The study will enroll 20 people a…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New drug shows promise for stem cell transplant complication
Disease control OngoingThis study tests a drug called acalabrutinib in 51 adults with moderate to severe chronic graft-versus-host disease (GVHD), a complication after a stem cell transplant. The goal is to see if the drug can control the disease when steroids have stopped working. Participants take th…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New PET tracer could spot hidden cancers
Diagnosis OngoingThis early study tests a new radioactive tracer called 68Ga-FAPI-46, which targets a protein (FAP) found around many tumors. About 26 people with various cancers will get a PET/CT scan using this tracer to see where it goes in the body. The goal is to learn if this tracer can hel…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 09:02 UTC
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Could a home device spot heart trouble in childhood cancer survivors?
Diagnosis OngoingThis study tests a portable, self-administered device that measures heart function in childhood cancer survivors, who are at risk for heart problems from past treatments. Researchers will compare the device's accuracy and ease of use in the clinic and at home against standard hos…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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Donor vaccine may shield transplant patients from dangerous virus
Prevention OngoingThis early-phase study tests whether vaccinating stem cell donors against cytomegalovirus (CMV) can prevent the virus from causing problems in blood cancer patients after a transplant. About 34 donor-recipient pairs are taking part. The vaccine is given to the donor before stem c…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC
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Brain training plus drug may ease chemo nerve damage
Symptom relief OngoingThis phase 2 trial tests whether combining neurofeedback (a brain-wave training therapy) with the drug duloxetine can better relieve nerve pain caused by chemotherapy than either treatment alone. About 336 cancer survivors with persistent nerve pain will be randomly assigned to o…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Speed of opioid infusion could change how cancer patients feel pain and drug effects
Symptom relief OngoingThis study looks at whether giving the painkiller hydromorphone slowly or quickly through an IV affects how well it controls cancer pain and how likely it is to be misused. About 84 hospitalized cancer patients with moderate to severe pain will receive both a slow and a fast infu…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE4 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New combo therapy aims to beat Cancer-Related insomnia
Symptom relief OngoingThis phase 2 trial tests whether combining cognitive behavioral therapy, a stimulant (methylphenidate), melatonin, and light therapy can improve sleep in cancer patients. About 68 patients currently on cancer treatment who have sleep problems will participate. The study measures …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Experimental drug aims to boost radiation against brain cancer
Symptom relief OngoingThis early-stage study tests an oral drug called ropidoxuridine (IPdR) combined with whole brain radiation in people whose cancer has spread to the brain. The goal is to find the safest dose and see if the drug makes radiation more effective at killing tumor cells. About 11 adult…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
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Exercise may soothe chemo nerve pain, trial hopes
Symptom relief OngoingThis study tests whether a structured exercise program can reduce chemotherapy-induced peripheral neuropathy (CIPN) — nerve damage causing pain, numbness, or tingling. About 133 cancer patients who received certain chemotherapies will either follow an exercise plan or receive sta…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a short talk therapy beat insomnia in cancer patients?
Symptom relief OngoingThis study tests whether a brief behavioral therapy (BBT-CI) or a healthy eating education program (HEAL) works better for reducing insomnia in cancer patients. About 400 adults with stage I-IV cancer who are currently receiving treatment and have sleep problems will take part. T…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a common mental health drug beat standard care for cancer appetite loss?
Symptom relief OngoingThis study tests whether olanzapine, a drug often used for mental health conditions, works better than megestrol acetate (the usual treatment) for improving appetite and preventing weight loss in people with advanced cancer. About 227 adults with cancer-related loss of appetite w…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Marijuana vs. opioids: which do cancer patients prefer for pain?
Symptom relief OngoingThis study looks at how cancer patients feel about using marijuana products (THC or CBD) compared to opioids for pain relief. Researchers will survey 200 adults with cancer-related pain who are already taking strong opioids. The goal is to understand patient preferences and perce…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Cancer breathlessness study: can opioids help you walk easier?
Symptom relief OngoingThis study tests if fast-acting opioids (fentanyl or morphine) can reduce shortness of breath during or after walking in 150 cancer patients who already take strong painkillers. Participants will take the drug or a placebo before a short walk test, and researchers will measure ch…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can a natural supplement soothe chemo nerve damage?
Symptom relief OngoingThis phase II trial tests whether a natural supplement called PEA can relieve nerve pain, numbness, and tingling caused by chemotherapy in cancer patients. About 88 adults who have had nerve symptoms for at least 3 months after chemo will take PEA or a placebo for 8 weeks. The st…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: Academic and Community Cancer Research United • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Cancer treatment gets personal: MATCH trial tests Gene-Guided drugs
Knowledge-focused OngoingThis phase II trial, called MATCH, is testing whether treating cancer based on the genetic makeup of a patient's tumor works better than standard treatments. Over 6,400 adults with advanced solid tumors, lymphomas, or multiple myeloma that have not responded to prior therapy are …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 06:00 UTC
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Teens with cancer help improve symptom tracking tool
Knowledge-focused OngoingThis study tests a symptom questionnaire designed for teenagers with cancer. Researchers will interview 41 adolescents aged 13-17 to see if the survey accurately captures their symptoms. The goal is to improve how doctors understand and manage symptoms in young cancer patients.
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Cancer patients and doctors share thoughts on virtual visits
Knowledge-focused OngoingThis study surveys 200 cancer patients and their doctors about their experiences with telemedicine (video visits) in radiation oncology. Participants answer a 10-minute questionnaire on satisfaction. The goal is to understand how well virtual care works for cancer follow-ups and …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Can a simple check spot hidden malnutrition in older cancer patients?
Knowledge-focused OngoingThis study looks at how well nutritional assessments can detect malnutrition in older adults with cancer. Researchers will follow 180 patients to see if nutrition status is linked to survival at 6 months and 1 year. The goal is to find better ways to identify and address malnutri…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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PPE vs video: which makes patients feel more cared for?
Knowledge-focused OngoingThis study looks at whether cancer patients feel their doctors show more empathy during in-person visits with protective gear (PPE) or during video calls without it. About 107 adults from MD Anderson's emergency center will share their views after a conversation with their doctor…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Money help for cancer patients: study tests financial navigation
Knowledge-focused OngoingThis study looks at whether a financial navigation program can help cancer patients and their partners manage the high costs of treatment. About 331 people with advanced cancer will get either the program or usual care. The goal is to see if this support reduces financial hardshi…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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What do parents really think about opioids for kids with cancer?
Knowledge-focused OngoingThis study surveys parents of children with cancer to learn about their attitudes and beliefs regarding the risks of using opioids for pain. Pain is common in pediatric cancer, and opioids are a key treatment, but parents often hesitate or underuse them. The goal is to fill a kno…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Pandemic's toll on cancer patients with neuropathy under the microscope
Knowledge-focused OngoingThis study looks at how the COVID-19 pandemic impacted the quality of life of 274 cancer patients who also have neuropathy (nerve pain). All participants had taken part in earlier clinical trials. Researchers want to see if there are differences between those who received a brain…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Brain waves reveal: do unresponsive patients hear us in their final days?
Knowledge-focused TerminatedThis study uses a brain wave test (EEG) to check if cancer patients who seem unresponsive in their last days can still hear or feel. Researchers will measure brain activity when sounds or words are played. The goal is to help families and doctors understand what patients may expe…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Lifestyle coaching aims to boost activity in cancer survivors
Knowledge-focused OngoingThis study tests whether personalized telehealth coaching can help young adult cancer survivors become more physically active and improve their diet. Researchers are enrolling 374 survivors aged 18-54 who are not very active. Participants receive one-on-one sessions with a clinic…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Cancer's hidden cost: study probes financial toxicity
Knowledge-focused OngoingThis study looks at how financial stress affects people recently diagnosed with cancer. Researchers will survey 625 patients to understand what factors contribute to financial hardship. The goal is to identify targets for future programs that could help ease the financial burden …
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Virtual team meetings aim to boost doctor engagement and efficiency
Knowledge-focused OngoingThis study looks at whether a special video mentoring program (called ECHO) can help diagnostic imaging doctors feel more connected and work more efficiently. About 36 doctors from MD Anderson will take part in regular online team meetings. The goal is to see if this approach imp…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Racial gap in cancer treatment? new study investigates immunotherapy outcomes
Knowledge-focused OngoingThis study is collecting blood, saliva, and health information from 2,100 Black and White cancer patients who are receiving immunotherapy (drugs that help the immune system fight cancer). The goal is to see if there are differences in side effects and how well the treatment works…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: University of Rochester NCORP Research Base • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Can a team of experts help older cancer patients bounce back after transplant?
Knowledge-focused OngoingThis study tests whether a program where older adults (65+) with blood cancer see a team of healthcare providers can help them stay fit and resilient after a stem cell transplant. The program includes health coaching, quality-of-life assessments, and questionnaires. The main goal…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Can a smartphone app get young cancer survivors moving? new study aims to find out.
Knowledge-focused OngoingThis study looks at whether a mobile health program combined with social media can help teens and young adults who survived childhood cancer become more physically active. About 387 participants will either use the program plus a fitness tracker or just the tracker alone. The goa…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Testosterone levels linked to brain health in new genetic analysis
Knowledge-focused OngoingThis study looks at whether having naturally low testosterone levels increases the risk of dementia, depression, or anxiety. Researchers will analyze genetic data from large biobanks (like UK Biobank) to see if certain genes linked to low testosterone are also linked to these men…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New dosing method for Kids' cancer drug aims to reduce side effects
Knowledge-focused OngoingThis study looks at a new method for giving the cancer drug vincristine to infants and young children. The goal is to see if this new way of calculating the dose leads to similar drug levels in the blood as the standard method used in older children. About 83 children up to 12 ye…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Cancer Patients' pandemic struggles revealed in new study
Knowledge-focused OngoingThis study looks at how the COVID-19 pandemic impacted the well-being and quality of life of over 13,000 cancer patients and survivors. Researchers used questionnaires to gather information on experiences like exposure, isolation, and financial disruptions. The goal is to underst…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can a smartphone app make radiation treatment less confusing?
Knowledge-focused OngoingThis pilot study tests a mobile app called oncpatient designed to help cancer patients navigate radiation therapy. The app provides easy-to-access information about treatment logistics and side effect management. Researchers will enroll 20 adults with cancer who are about to star…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Why are transplant survivors at higher heart risk? new study seeks answers
Knowledge-focused OngoingThis study looks at how well the heart, lungs, and muscles work together in people who have had a stem cell transplant. Researchers want to find out why transplant survivors have a higher risk of heart disease. About 350 adults with blood cancers will be followed for two years af…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Withdrawn study sought to identify which cancer patients could safely be treated at home for fever
Knowledge-focused TerminatedThis study was designed to look at cancer patients with neutropenic fever (fever with low white blood cells) to see how many had serious complications. The goal was to help decide which patients might be safely treated at home instead of in the hospital. However, the study was wi…
Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:35 UTC