Targeted drug shows promise for rare genetic cancers
NCT ID NCT04439331
First seen Nov 19, 2025 · Last updated May 13, 2026 · Updated 16 times
Summary
This study is for people with advanced cancers that have a specific genetic change called an NF2 mutation. The drug defactinib blocks a protein that may help these cancers grow. Researchers want to see if it can shrink tumors or stop them from getting worse. About 35 adults are taking part in this phase 2 trial.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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ECOG-ACRIN Cancer Research Group
Philadelphia, Pennsylvania, 19103, United States
Conditions
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