REFRACTORY MALIGNANT SOLID NEOPLASM
Clinical trials for REFRACTORY MALIGNANT SOLID NEOPLASM explained in plain language.
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Scientists re-engineer Patients' own cells to hunt advanced cancers
Disease control Recruiting nowThis early-phase study is testing a new type of cell therapy for people with advanced solid tumors, including melanoma, that have spread and are not responding to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack c…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: Anusha Kalbasi • Aim: Disease control
Last updated Apr 01, 2026 16:55 UTC
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Groundbreaking pill trial offers hope for tough liver cancers
Disease control Recruiting nowThis is the first human study of an experimental oral medication called AU409 for people with advanced liver cancers or other solid tumors that have spread to the liver. The main goal is to find the safest and most effective dose by testing it in a small group of patients whose c…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New Triple-Threat cancer therapy enters human testing
Disease control Recruiting nowThis study is testing whether combining three different cancer drugs is safe and effective for treating advanced solid tumors that have spread or returned after standard treatments. The three drugs work in different ways: one helps the immune system attack cancer, one blocks tumo…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New hope for kids with tough cancers: experimental drug combo enters trial
Disease control Recruiting nowThis study is testing a new two-drug combination for children, teens, and young adults whose solid tumors or a rare liver cancer called fibrolamellar carcinoma have come back or stopped responding to standard treatments. The main goals are to find the safest and most effective do…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New hope drug enters human testing for Tough-to-Treat cancers
Disease control Recruiting nowThis is the first human study of an experimental oral drug called AOH1996 for patients with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the safest dose and understand how the body processes the drug. Researchers will enrol…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New drug duo targets Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing the safety and effectiveness of a new two-drug combination for people with advanced solid tumors, including pancreatic cancer, that have spread or stopped responding to standard treatments. The trial aims to find the best dose and see if the drugs can help c…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for kids with aggressive brain tumors: experimental drug trial opens
Disease control Recruiting nowThis early-stage trial is testing a new drug called CBL0137 in children and young adults (ages 1-21) whose solid tumors, brain tumors, or lymphoma have come back or stopped responding to standard treatments. The main goals are to find the safest dose and see if the drug can help …
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for kids with tough cancers: experimental drug trial opens
Disease control Recruiting nowThis study is testing a new drug called tegavivint in children, teens, and young adults whose solid tumors or lymphomas have come back or haven't responded to other treatments. The main goals are to find the safest dose, understand the side effects, and see if the drug can help s…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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First human test for promising new cancer pill
Disease control Recruiting nowThis is an early safety study for a new drug called TAK-243 in adults with advanced solid tumors or lymphoma. The main goal is to find the safest dose and understand the side effects. Researchers will give the drug to about 95 patients and closely monitor how their bodies handle …
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 16, 2026 15:23 UTC
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New cancer pill targets tumor growth enzyme in first human trial
Disease control Recruiting nowThis is the first study in people testing a new oral drug called MTI-301 for advanced solid cancers that have spread or cannot be removed by surgery. The main goal is to find the highest safe dose and understand the drug's side effects in 42 patients whose cancers have not respon…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 09, 2026 14:26 UTC
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New hope for kids with tough cancers: trial tests Double-Team drug strategy
Disease control Recruiting nowThis study is testing two different drug combinations to find safe doses and see if they can help control cancer in children and young adults whose solid tumors have come back or haven't responded to treatment. In the first part, participants will be assigned to receive either On…
Matched conditions: REFRACTORY MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC