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Can a simple home breathing test catch lung trouble early in transplant patients?

NCT ID NCT05250037

Ongoing Knowledge-focused Sponsor: Fred Hutchinson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study follows 250 people who have had a donor stem cell transplant to see if respiratory viruses lead to a lung condition called bronchiolitis obliterans syndrome (BOS). Participants use a handheld device at home to measure lung function and provide nasal swabs and blood samples. The goal is to understand the link between viruses and lung damage, and whether home monitoring can help diagnose problems sooner.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could show that home spirometry helps detect lung problems earlier in transplant patients, potentially leading to better monitoring and treatment.
What could go wrong
This is an observational study, not a treatment trial. It may not prove that viruses cause lung disease, and home spirometry might not be accurate enough to replace clinic tests.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bronchiolitis obliterans syndrome hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIOLITIS OBLITERANS SYNDROME HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Stanford Cancer Institute

    Palo Alto, California, 94304, United States

  • University of Michigan Cancer Center

    Ann Arbor, Michigan, 48109, United States

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