Targeted drug shows promise for rare Mutation-Driven cancers

NCT ID NCT04439357

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 29 times

Summary

This study tested the drug trametinib in 4 people with advanced cancers that have GNAQ or GNA11 mutations. Trametinib blocks certain proteins that help these cancer cells grow. The goal was to see if the drug could shrink tumors or stop them from growing.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.