New drug trial offers hope for stem cell transplant complications

NCT ID NCT04198922

Summary

This study is testing whether the drug acalabrutinib can help control chronic graft-versus-host disease in adults who have had a stem cell transplant. The trial involves 51 participants whose condition worsened despite steroid treatment. Patients take the medication orally for up to two years while researchers measure how well it controls their symptoms and improves their quality of life.

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Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14203, United States

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

Conditions

Explore the condition pages connected to this study.