New hope for hard-to-treat cancers with gene amplification?

NCT ID NCT04439201

First seen Mar 17, 2026 · Last updated Apr 30, 2026 · Updated 8 times

Summary

This study tests a drug called palbociclib in people with advanced cancers that have extra copies of certain genes (CCND1, 2, or 3). The drug blocks proteins that help cancer grow. Researchers want to see if it can shrink tumors or stop them from getting worse. About 40 adults with solid tumors or lymphomas that haven't responded to other treatments are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.