Targeted therapy shows promise for rare HER2-Positive cancers

NCT ID NCT04439110

First seen Nov 21, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests a drug called ado-trastuzumab emtansine in people with advanced cancers that have too many HER2 receptors (HER2 amplification), except breast and stomach cancers. The drug combines an antibody that targets HER2 with a chemotherapy agent to kill cancer cells. Researchers want to see if it can shrink tumors or stop them from growing. About 38 adults with various hard-to-treat cancers are taking part.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.