Targeted drug shows promise for rare cancers with ROS1 mutation

NCT ID NCT04439253

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 24 times

Summary

This study tested the drug crizotinib in 4 people with advanced cancers (like lymphoma or solid tumors) that have a specific genetic change called ROS1 translocation. The drug blocks a protein that helps cancer cells grow. The goal was to see if the drug could shrink tumors or stop them from growing. This is a small, early-phase study to gather information on how well the treatment works.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.