GENERAL ANESTHESIA

This study tested two different ways of using a breathing machine during emergency abdominal surgery. One method used higher air pressure to keep the lungs open, while the other used lower pressure to avoid overstretching the lungs. The goal was to see which approach led to fewer…

This study looked at whether the drug dobutamine helps people with septic shock who are having surgery. Septic shock is a life-threatening condition where blood pressure drops dangerously low. The researchers wanted to see if dobutamine could reduce kidney injury, organ failure, …

This trial tests whether a single dose of the anti-inflammatory drug dexamethasone, given during jaw surgery, can lessen pain, swelling, and trouble opening the mouth afterward. About 60 people having wisdom tooth removal or cyst surgery under general anesthesia will take part. T…

This trial tests whether a device that tracks heart rate patterns can help doctors give just the right amount of anesthesia during gallbladder removal surgery. The goal is to use less anesthetic and pain medicine, helping patients wake up faster and leave the recovery room sooner…

This study tested a way to keep people asleep during lung surgery without using strong opioid painkillers. Instead, they used a drug called esketamine along with standard anesthetics. The goal was to see if this approach could help patients breathe better during the operation. Th…

This study tested whether showing patients a short educational video before a bronchoscopy under general anesthesia could reduce their anxiety more than standard verbal instructions. Fifty-eight adults scheduled for the procedure were randomly assigned to watch the video or recei…

This study tested a special monitor that tracks the body's pain balance during general anesthesia for laparoscopic (keyhole) surgery. The goal was to see if using this monitor to adjust painkiller doses could reduce side effects like low blood pressure, slow heart rate, or sudden…

This study looked at 60 children aged 3-8 years who needed a procedure to close a hole in their heart. Researchers compared general anesthesia to a lighter sedation combined with numbing medicine at the catheter site. They measured heart rate and blood pressure to see which appro…

This study tested a new sedative called ciprofol against the standard drug propofol for general anesthesia in 124 older adults undergoing transcatheter aortic valve replacement (TAVR). The goal was to see if ciprofol causes fewer episodes of low blood pressure after anesthesia. R…

This study tested whether avoiding opioids during gallbladder surgery could improve recovery. 101 patients received either opioid-free anesthesia (using lidocaine and dexmedetomidine) or standard opioid anesthesia. The opioid-free group had less pain after surgery, needed fewer p…

This study tested whether giving magnesium sulfate during laparoscopic hysterectomy can lower the amount of painkillers needed during and after surgery. Sixty adults undergoing the procedure received either magnesium or a placebo. The goal was to see if magnesium could reduce opi…

This phase 3 trial tested whether a new drug called HSK3486 works as well as the standard drug propofol for putting adults under general anesthesia before elective surgery. About 400 participants received either HSK3486 or propofol to see if it safely and effectively induces anes…

This study tested a new anesthetic called HSK3486 to see if it works as well as the standard drug propofol for putting adults to sleep before elective surgery. The trial involved 465 participants and compared success rates of inducing general anesthesia. The goal is to provide a …

This study tested whether storing a laryngeal mask airway (a breathing tube used during general anesthesia) at a cold temperature (10-12°C) instead of room temperature (22-25°C) could reduce sore throat after surgery. 172 adults having elective surgery were randomly assigned to o…

This study looked at how a common anesthesia gas, sevoflurane, affects brain wave patterns during surgery. Researchers monitored 34 women having gynecological surgery to see if certain brain wave spikes occur. The goal was to better understand the effects of sevoflurane on the br…

This completed study looked at 60 adults having leg surgery with a tourniquet to see if spinal or general anesthesia better maintains blood flow in the leg. Researchers used a light-based sensor to measure tissue oxygen levels. The goal was to understand which method might reduce…

This study looked at 100 pregnant women having planned C-sections to see if the time it takes to deliver the baby affects the baby's cord blood pH and base excess—measures of newborn health. Researchers compared general and spinal anesthesia to see if the type of anesthesia chang…

This study looked at whether a simple scoring method called PRST (which checks blood pressure, heart rate, sweating, and tears) can accurately measure how deep a patient's anesthesia is during surgery. 183 adults having elective surgery were monitored either with PRST alone or PR…

This study compared penile length in 200 adult men undergoing cystoscopy under spinal anesthesia versus general anesthesia. Researchers measured length and asked surgeons to rate satisfaction with access. The goal was to see if anesthesia choice affects penile size during the pro…

This study looked at how different ventilator pressure levels (PEEP) affect blood flow and brain function in 78 elderly patients having gallbladder surgery. Patients were split into three groups, each receiving a different PEEP level. The goal was to see which level best maintain…

This completed study looked at 204 patients who had a kidney removed (nephrectomy) to find out what factors might lead to chronic pain lasting months or years after surgery. Researchers measured pain levels at 1 hour, 3 months, and 1 year after the operation using a simple 0-to-1…

This observational study looked at a new measure called eMAC that combines the effects of inhaled and IV anesthetics to gauge how deep a patient is under anesthesia. Researchers observed 60 adults having elective surgery, recording standard vital signs and depth monitors without …

This study looked at whether a new anesthetic drug called HSK3486 has abuse potential similar to or lower than propofol, a common anesthetic. It involved 43 healthy adults who occasionally use depressant drugs recreationally. The goal was to find the right dose and compare how th…

This study tested two methods of removing a breathing tube after digestive surgery to see which one helps patients breathe better. 208 adults having surgery lasting over an hour took part. One group had the tube removed the usual way, and the other had it removed while still conn…

This study looked at two different brands of stainless steel crowns used to fix cavities in children aged 2 to 8 years old. All children were treated under general anesthesia at a dental school. Researchers checked how well the crowns stayed in place and kept the gums healthy, an…

This study looked at 110 children aged 2-10 having surgery under general anesthesia. Researchers compared two common breathing machine modes (volume-controlled vs. pressure-controlled) to see which one leads to less lung collapse (atelectasis). They used lung ultrasound to check …

This study looked at whether using ultrasound to check what's in a child's stomach before emergency surgery can help doctors choose a safer way to give anesthesia. 146 children took part. The goal was to see if the ultrasound results led doctors to change their usual approach, po…