GENERAL ANESTHESIA

This study compared two ways of using a breathing machine during emergency abdominal surgery to see which one leads to fewer lung problems and deaths. Over 700 adults took part. One method used higher air pressure and extra breaths to open the lungs, while the other used lower pr…

This study tested whether a heart medication called dobutamine improves outcomes for patients with septic shock who need surgery under general anesthesia. Septic shock causes dangerously low blood pressure, and anesthesia can further weaken the heart. The study involved 584 adult…

This study tested a new medicine called HSK3486 to see if it works as well as propofol for putting adults to sleep before planned surgery. About 465 people took part. The goal was to safely and quickly achieve the right level of unconsciousness without needing extra rescue drugs.

This study tested a new drug called HSK3486 to see if it works as well as the standard drug propofol for putting adults to sleep before planned surgery. About 400 people took part. The goal was to safely and effectively start general anesthesia without needing extra rescue drugs.

This study tested a new sedative called ciprofol against the standard drug propofol for patients undergoing a minimally invasive heart valve replacement (TAVR). The goal was to see if ciprofol causes fewer drops in blood pressure after anesthesia. 124 older adults (ages 60-85) pa…

This study looked at whether giving magnesium sulfate through a vein during laparoscopic hysterectomy surgery can lower the amount of strong pain medicine (opioids) needed during and after the operation. Sixty adults having this surgery took part. The goal was to see if magnesium…

This study tested whether avoiding opioids during gallbladder surgery could improve recovery. 101 adults having laparoscopic gallbladder removal were randomly assigned to receive either opioid-free anesthesia (using lidocaine and dexmedetomidine) or standard opioid-based anesthes…

This study looked at 60 children aged 3-8 years who needed a procedure to close a hole in their heart. Researchers compared standard general anesthesia to a lighter sedation using two medicines (dexmedetomidine and ketamine) plus numbing at the catheter insertion site. They measu…

This study tested whether using esketamine instead of opioids during lung nodule surgery could improve lung function. 84 adults having lung surgery were randomly assigned to receive either esketamine or standard opioid anesthesia. The main goal was to measure lung compliance, or …

This study tested whether a special monitor (called ANI) that tracks the body's pain balance during anesthesia can help doctors give just the right amount of pain medicine. 37 adults having laparoscopic surgery took part. The goal was to see if using the monitor reduced episodes …

This study looked at 110 children aged 2-10 having surgery under general anesthesia. It compared two common breathing machine modes (volume-controlled vs. pressure-controlled) to see which one causes less lung collapse (atelectasis). Doctors used lung ultrasound to check for coll…

This study followed 204 adults who had a kidney removed to find out why some develop chronic pain lasting months or years. Researchers measured pain levels right after surgery, at 3 months, and at 1 year. They also looked at factors like age, smoking, and pain medicine use to ide…

This study looked at whether a new anesthetic drug called HSK3486 has potential for abuse. It involved 43 healthy adults who occasionally use depressants. Researchers compared HSK3486 to another anesthetic, propofol, to see how likely people are to misuse it.

This study looked at 60 adults having leg surgery with a tourniquet to see if spinal or general anesthesia better preserves blood flow in the leg. Researchers used a special light sensor to measure tissue oxygen levels. The goal was to understand which method might reduce tissue …

This study looked at 78 older adults (65+) having gallbladder surgery to see how different ventilator pressure levels affect blood flow and thinking skills. Researchers measured blood flow in the arm and brain, and tested memory and attention before and after surgery. The goal wa…

This study tested two methods of removing a breathing tube after digestive surgery to see which one helps patients breathe better. 208 adults having surgery lasting over an hour took part. One group had the tube removed the usual way, and the other had it removed while still conn…

This study looked at two different brands of stainless steel crowns used to fix cavities in children's baby teeth. The children, aged 2 to 8, had the crowns placed while under general anesthesia. Researchers checked how well the crowns stayed in place and kept the gums healthy, a…

This study looked at whether storing a breathing tube (laryngeal mask airway) at a cooler temperature (10-12°C) versus room temperature (22-25°C) affects sore throat after surgery. 172 adults having elective surgery under general anesthesia took part. Researchers checked for sore…

This study looked at a new measure called eMAC that combines the effects of different anesthesia drugs to gauge how deep a patient's anesthesia is during surgery. Researchers observed 60 adults having planned surgeries and recorded standard anesthesia readings without changing an…

This study looked at whether using ultrasound to check children's stomach contents before emergency surgery can help doctors choose a safer way to give anesthesia. The goal is to reduce the risk of stomach contents entering the lungs. 146 children aged 0 to 18 took part, and doct…