GENERAL ANESTHESIA

This study tested whether adding a heart medication called dobutamine to standard care improves outcomes for patients with severe septic shock who need surgery under general anesthesia. It involved 584 adult surgical patients to see if the drug could help protect the heart and ki…

This study tested if a new drug called HSK3486 works as well as the standard drug propofol for putting adults to sleep before elective surgery. 465 adults scheduled for surgery were randomly given either the new drug or propofol in a blinded study. The main goal was to see if HSK…

This study compared two brands of stainless steel crowns used to fix cavities in young children's teeth during procedures under general anesthesia. Researchers followed 54 children aged 2-8 for at least six months to see which crown stayed on better and caused fewer problems. The…

This study tested if a new drug called HSK3486 works as well as the standard drug propofol for putting adults to sleep before elective surgery. 400 adults having planned surgery were randomly assigned to receive either the new drug or propofol in a blinded study. The main goal wa…

This study tested whether using a simple ultrasound scan to check if a child's stomach is empty before emergency surgery could help doctors choose a safer anesthesia method. Researchers scanned 146 children aged 0-18 before their operations to see if the scan results changed how …

This study tested a new anesthetic drug called ciprofol during a minimally invasive heart valve replacement procedure. Researchers compared it to the standard drug propofol in 124 older patients to see if ciprofol causes fewer drops in blood pressure and other side effects. The g…

This study tested whether giving magnesium sulfate through an IV during surgery could help reduce pain and the need for strong opioid painkillers afterward. It involved 60 women having a laparoscopic hysterectomy. Researchers compared pain levels and medication use between those …

This study compared two ways to keep children comfortable and stable during a procedure to close a hole in the heart. It tested whether a lighter sedation method works as well as general anesthesia for 3-8 year olds. Researchers measured heart rate, blood pressure, recovery time,…

This study investigated whether storing the breathing masks used during general anesthesia at cooler temperatures could reduce patients' sore throats after surgery. Researchers compared masks stored at room temperature (22-25°C) against those stored chilled (10-12°C) in 172 adult…

This study compared two types of anesthesia for people having their gallbladder removed. One method used strong painkillers (opioids), while the other used a combination of different drugs to avoid opioids. The goal was to see which approach led to less pain, nausea, and a smooth…

This study tested whether using an anesthetic drug called esketamine, instead of traditional opioid painkillers, could improve recovery for patients having minimally invasive lung surgery. It involved 84 adults undergoing surgery to remove lung nodules. Researchers compared the e…

This study tested if removing a patient's breathing tube using a specific 'positive pressure' technique could help prevent low oxygen levels after major abdominal surgery. Researchers compared this new method to the standard way of removing the tube in 208 adult patients. The goa…

This study aimed to understand why some people develop long-lasting pain after kidney removal surgery. Researchers followed 204 patients for a year, tracking their pain levels and many personal and surgical details. The goal was to identify which factors increase the risk of chro…

This study aimed to find out which of two common breathing machine settings causes less lung collapse in children under general anesthesia. Researchers used safe, bedside ultrasound scans to compare the two methods in 110 children aged 2-10 having elective surgery. The goal was t…

This study observed 60 adults having planned surgery to test a new way of measuring how deeply asleep they are under anesthesia. The new measurement, called eMAC, is designed to work with all types of anesthesia drugs, unlike the current standard. Researchers compared eMAC to the…

This study aimed to understand if a new anesthetic drug called HSK3486 has potential for abuse. Researchers compared its effects to a common anesthetic, propofol, in healthy adults who had previously used recreational depressant drugs. The goal was to gather safety data on the dr…