New anesthetic may offer safer sedation for heart valve patients
NCT ID NCT05881291
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new sedative called ciprofol against the standard drug propofol for general anesthesia in 124 older adults undergoing transcatheter aortic valve replacement (TAVR). The goal was to see if ciprofol causes fewer episodes of low blood pressure after anesthesia. Researchers measured blood pressure changes in the first 15 minutes after sedation and tracked side effects like injection pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ciprofol
What this could lead to
If successful, ciprofol could offer a safer alternative to propofol for anesthesia in heart valve replacement, with fewer drops in blood pressure.
What could go wrong
This is a small, completed phase 4 trial with 124 patients. Results may not apply to all patients, and ciprofol's benefits over propofol may be modest.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Second Affiliated Hospital of Zhejiang University anesthesiology department
Hangzhou, Zhejiang, 310000, China