HEMODYNAMICS

This study tests whether ivabradine, a drug that slows heart rate without weakening the heart's pumping strength, can help people with sepsis. Sepsis is a life-threatening infection that often causes a dangerously fast heart rate. The trial will enroll 172 adults in intensive car…

This study compares two monitors used during laparoscopic abdominal surgery to see which one better predicts whether giving fluids will help the heart pump more effectively. About 300 adults having elective surgery will receive small fluid boluses, and the monitors' readings will…

This study tests whether wearing a virtual reality headset with calming scenes can reduce anxiety and stress during a cesarean section as well as a sedative drug called dexmedetomidine. Fifty-two women having planned C-sections will be randomly assigned to receive either the VR h…

This study compares two methods of releasing a tourniquet (a tight band that stops blood flow) during arm surgery in patients with high blood pressure. The goal is to see which method causes less of a sudden drop in blood pressure. The trial will include 68 adults whose blood pre…

This study looks at whether giving the painkiller nalbuphine at different times during knee replacement surgery can better control pain and keep the heart stable in patients aged 65 and older. About 162 participants will receive nalbuphine either during anesthesia or after cement…

This study looks at whether using less fresh gas during anesthesia (low-flow anesthesia) changes heart rate, blood pressure, and oxygen levels in adults having open-heart surgery. Researchers will monitor 80 participants before and during surgery. The goal is to understand how th…

This study watches 160 heart surgery patients who take blood pressure medications to see if taking more than one drug increases the risk of a sudden drop in blood pressure after anesthesia. The researchers will measure how low blood pressure goes and how long it stays low. No new…

This study tracks 242 pregnant women to measure how their heart rate and blood pressure change from the third month of pregnancy through the postpartum period. Researchers use non-invasive tests like ECG and blood pressure cuffs to understand the body's natural adjustments. The g…

This study tests 99 adults having planned surgery to find the right remifentanil dose that keeps heart rate and blood pressure stable when a breathing tube is inserted. Patients receive either lidocaine, sufentanil, or a placebo alongside etomidate to see which combination works …

This study looks at 80 critically ill ICU patients who need tube feeding. Doctors will use a bedside ultrasound to measure blood flow in the gut artery after feeding starts. The goal is to see if changes in blood flow can predict gut injury, so feeding can be adjusted to be safer…