New anesthetic HSK3486 put to the test: will it be safer than propofol?

NCT ID NCT07404306

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a new anesthetic drug called HSK3486 has abuse potential similar to or lower than propofol, a common anesthetic. It involved 43 healthy adults who occasionally use depressant drugs recreationally. The goal was to find the right dose and compare how the drugs make people feel, to help guide future safe use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HSK3486

What this could lead to

If successful, this could help determine whether HSK3486 is a safer anesthetic with lower abuse potential than current options.

What could go wrong

This is an early Phase 1 study with only 43 healthy volunteers, not patients. Results may not predict real-world abuse or safety in surgical settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ICON (LPRA) - Salt Lake

    Salt Lake City, Utah, 84124, United States