New sleep drug for surgery put to the test

NCT ID NCT05486416

Completed Symptom relief Sponsor: Haisco-USA Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new anesthetic called HSK3486 to see if it works as well as the standard drug propofol for putting adults to sleep before elective surgery. The trial involved 465 participants and compared success rates of inducing general anesthesia. The goal is to provide a safe and effective alternative for patients undergoing planned operations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HSK3486 injectable emulsion

What this could lead to

If successful, HSK3486 could offer a new option for putting people to sleep before surgery, possibly with fewer side effects than current anesthetics.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. Even if non-inferior, it may not offer major advantages over propofol, and individual responses can vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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GENERAL ANESTHESIA

Contacts and locations

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Locations

Atlanta Center for Medical Research

Atlanta, Georgia, 30331, United States
Clinical Trials of Texas, LLC

San Antonio, Texas, 78229, United States
Duke University Medical Center (DUMC)

Durham, North Carolina, 27710, United States
EBGS Clinical Research Center

Snellville, Georgia, 30078, United States
Endeavor Clinical Trials, LLC

San Antonio, Texas, 78240, United States
First Surgical Hospital

Bellaire, Texas, 77401, United States
ForCare Clinical Research

Tampa, Florida, 33613, United States
Gulfcoast Research Institute

Sarasota, Florida, 34232, United States
Helen Keller Hospital

Sheffield, Alabama, 35660, United States
Hospital Clinic De Barcelona

Barcelona, Spain
Hospital Clinico Universitario de Valencia (CHUV)

Valencia, Spain
Hospital General Universitario De Ciudad Real

Ciudad Real, Spain
Legent Orthopedic Hospital

Carrollton, Texas, 75006, United States
M3-Emerging Medical Research, LLC

Durham, North Carolina, 27704, United States
Memorial Hermann Village

Houston, Texas, 77043, United States
Michigan Medicine

Ann Arbor, Michigan, 48109, United States
North Alabama Medical Center

Florence, Alabama, 35630, United States
Państwowy Instytut Medyczny Mswia - Klinika Anestezjologii I Intensywnej Terapii

Warsaw, Poland
Phoenix Clinical Research, LLC

Tamarac, Florida, 33321, United States
Spsk Nr 1 Im. Prof. S. Szyszko

Zabrze, Poland
The Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
The Ohio State University Wexner Medical Center - University Hospital

Columbus, Ohio, 43210, United States
The University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States
U of L Health, University of Louisville Hospital

Louisville, Kentucky, 40202, United States
Universidad de Navarra - Clinica Universidad de Navarra en Pamplona

Pamplona, Spain
University of Iowa Hospitals and Clinics (Dept of Anesthesia)

Iowa City, Iowa, 52242, United States
University of Miami Hospital

Miami, Florida, 33136, United States
Uniwersytecki Szpital Kliniczny W Opolu

Opole, Poland