GASTRIC ADENOCARCINOMA

This study tested whether adding the drug AK104 to standard chemotherapy helps people with advanced stomach or gastroesophageal junction cancer live longer. It involved 610 adults who had not received prior treatment. The goal was to see if the combination improves survival and s…

This study tested a combination of three drugs—regorafenib, nivolumab, and chemotherapy—in 30 people with advanced or recurrent stomach, gastroesophageal junction, or esophageal cancer that could not be removed by surgery. The goal was to see if the combination was safe and effec…

This early-phase study tested a new drug called TPST-1495, alone or with pembrolizumab, in 89 people with advanced solid tumors (like colorectal, lung, or head and neck cancer) that had stopped responding to standard treatments. The main goal was to find the safest dose and check…

This study tested a combination of three drugs—trastuzumab deruxtecan (a targeted therapy), nivolumab (an immunotherapy), and chemotherapy—in 30 people with advanced HER2-low stomach or gastroesophageal junction cancer who had not received prior treatment. The goal was to find th…

This study tested whether combining two drugs, TAS 102 and ramucirumab, is safe and works for people with advanced stomach or gastroesophageal junction cancer that no longer responds to other treatments. 23 participants were enrolled. The goal was to see how long they lived and h…

This early-stage study tested a new drug called SGN-B6A in 6 Chinese adults with advanced solid tumors (lung, head/neck, esophageal, or stomach cancers) that had stopped responding to standard treatments. The main goal was to check the drug's safety and side effects, and to see h…

This study looked at 258 adults with untreated oeso-gastric cancer to understand why some wait longer to see a doctor after noticing symptoms. Researchers examined social, economic, and personal factors that may cause delays. The goal is to help find ways to encourage earlier dia…

This study looked back at 96 patients with advanced stomach cancer to compare two surgeries: removing only the upper part of the stomach (proximal gastrectomy) versus removing the whole stomach (total gastrectomy). The goal was to see which surgery leads to better long-term survi…