New antibody drug targets Hard-to-Treat gut cancers in early trial

NCT ID NCT05411133

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 28 times

Summary

This early-stage study tested a new drug called cabotamig in 33 adults with advanced gastrointestinal cancers (like stomach, liver, or bowel cancer) that had stopped responding to standard treatments. The drug works by attaching to a marker on cancer cells and helping the immune system attack them. The main goals were to check safety and see how the drug behaves in the body, not to prove a cure.

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Contacts and locations

Locations

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Southern Oncology Clinical Research Unit

    Adelaide, Australia

  • St George Private Hospital

    Sydney, Australia

Conditions

Explore the condition pages connected to this study.