New hope for advanced gut cancers? early trial tests targeted antibody

NCT ID NCT05411133

First seen Nov 01, 2025 · Last updated Jun 03, 2026 · Updated 34 times

Summary

This early-stage study tested a new drug called cabotamig in 33 adults with advanced cancers of the digestive system (like colon, pancreas, or liver) that had stopped responding to standard treatments. The goal was to see if the drug is safe and how it affects the body and tumors. Participants needed to have a specific marker (CDH17) on their cancer cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Southern Oncology Clinical Research Unit

    Adelaide, Australia

  • St George Private Hospital

    Sydney, Australia

Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus cholangiocarcinoma digestive system neoplasm gastric neoplasm Liver Neoplasms pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.