New combo therapy targets tough stomach cancer

NCT ID NCT05419362

First seen Jan 04, 2026 · Last updated May 09, 2026 · Updated 16 times

Summary

This study tested a new combination of two drugs, GEN-001 and avelumab, in 42 people with advanced stomach or gastroesophageal junction cancer that had not responded to at least two prior treatments. The goal was to see if the combination could shrink tumors or slow cancer growth. Participants had to have a specific protein (PD-L1) on their cancer cells. The study is now complete, and results will show if this approach is safe and effective.

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Contacts and locations

Locations

  • Ajou University Hospital

    Gyeonggi-do, South Korea

  • Asan Medical Center

    Seoul, South Korea

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Gyeonggi-do, South Korea

  • Yonsei University Health System, Severance Hospital

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.