New triple therapy aims to beat drug-resistant cancers

NCT ID NCT05383482

First seen Nov 17, 2025 · Last updated May 13, 2026 · Updated 20 times

Summary

This study tested a combination of three drugs (afuresertib, sintilimab, and chemotherapy) in 22 adults with solid tumors like lung, cervical, or stomach cancer that had stopped responding to prior immunotherapy. The goal was to find the safest dose and see if the combo could shrink tumors. The study is complete, but results are not yet reported.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Chongqing Cancer Hospital

    Chongqing, Chengdu, China

  • Jilin Cancer Hospital

    Changchun, Jilin, China

  • West China Second University Hosital, Sichuan University

    Chengdu, Sichuan, China

  • Zhongshan Hospital, Fudan University

    Shanghai, Shanghai Municipality, China

Conditions

Explore the condition pages connected to this study.