New stomach cancer combo shows promise in early trial
NCT ID NCT00512304
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 2 study tested a combination of chemotherapy (FOLFIRI) and radiation with 5-fluorouracil in 63 patients with gastric cancer. The treatment was given either before or after surgery to remove the tumor. The goal was to see if this approach is feasible and less toxic than older regimens. The study focused on patients with locally advanced disease (T3 or N+) who had not yet developed metastases.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FOLFIRI chemotherapy plus 5-fluorouracil and radiation
What this could lead to
If successful, this could point toward a more effective and less toxic treatment plan for gastric cancer patients after surgery.
What could go wrong
This is a small, early-phase feasibility study, so results may not apply to all patients. The treatment still involves significant side effects from chemotherapy and radiation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University hospital
Rouen, 76031, France