New drug duo shows promise for tough cancers

NCT ID NCT05235542

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested two experimental drugs (AK104 and AK117) together, sometimes with chemotherapy, in 128 people with advanced solid tumors. The goal was to see if the combination is safe and can shrink tumors. It focused on patients with stomach, esophageal, or other advanced cancers that had stopped responding to standard treatments.

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Conditions

The condition(s) this trial relates to.

cancer esophageal squamous cell carcinoma gastric adenocarcinoma gastroesophageal junction adenocarcinoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Renji Hospital

    Shanghai, China