Immunotherapy-Chemo cocktail aims to tame stomach cancer

NCT ID NCT03813784

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 3 trial tested whether adding the immunotherapy drug camrelizumab to standard chemotherapy, followed by camrelizumab plus the targeted drug apatinib, helps people with advanced stomach or gastroesophageal junction cancer live longer. The study enrolled 885 participants who had not received prior treatment for advanced disease. The goal is to see if this combination improves overall survival compared to chemotherapy alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

camrelizumab (an immunotherapy drug) combined with capecitabine and oxaliplatin (chemotherapy), followed by camrelizumab plus apatinib (a targeted therapy)

What this could lead to

If successful, this combination could offer a new first-line treatment option that helps people with advanced gastric or GEJ cancer live longer and control their disease better.

What could go wrong

This is a Phase 3 trial, but results are not yet published. The combination may cause significant side effects, and not all patients may benefit, especially those with low PD-L1 levels.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GASTRIC CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Cancer Hospital, Peking University

    Beijing, Beijing Municipality, China