New hope for stomach cancer: drug cocktail shows promise in early trial

NCT ID NCT07529613

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a mix of three drugs—trastuzumab deruxtecan (a targeted therapy), nivolumab (an immunotherapy), and chemotherapy—in 30 people with untreated HER2-low stomach or gastroesophageal junction cancer. The goal was to first find a safe dose and then see how well it shrinks tumors. While not a cure, the approach aims to control the disease and improve outcomes for a type of cancer that has few treatment options.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan