New hope for stomach cancer patients with low HER2 levels?

NCT ID NCT07529613

First seen Apr 17, 2026 · Last updated May 08, 2026 · Updated 5 times

Summary

This study tested a combination of three drugs—trastuzumab deruxtecan (a targeted therapy), nivolumab (an immunotherapy), and chemotherapy—in 30 people with advanced HER2-low stomach or gastroesophageal junction cancer who had not received prior treatment. The goal was to find the safest dose and see how well the combo shrinks tumors. While promising, this approach aims to control the disease, not cure it, and ongoing treatment is needed.

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Contacts and locations

Locations

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

Conditions

Explore the condition pages connected to this study.