ENDOMETRIAL CANCER

This study tested a shorter course of pelvic radiation after hysterectomy in 25 women with advanced endometrial cancer. The goal was to see if the shorter treatment causes fewer side effects while still controlling the cancer as well as the standard 5-6 week radiation. Participan…

This study tested whether taking the drug selinexor after chemotherapy can help keep advanced or recurrent endometrial cancer from growing back. About 263 women whose cancer had shrunk or disappeared after chemo were randomly assigned to receive selinexor or a placebo once a week…

This study tested a new drug combination (MK-4280A) in 163 people with either a type of skin cancer (cutaneous squamous cell carcinoma) or endometrial cancer. The goal was to see if the treatment could shrink or eliminate tumors. Participants received either the new combination o…

This early-phase study tested a new drug called TPST-1495, alone or with pembrolizumab, in 89 people with advanced solid tumors (like colorectal, lung, or head and neck cancer) that had stopped responding to standard treatments. The main goal was to find the safest dose and check…

This study tested a combination of three drugs (bevacizumab, atezolizumab, and rucaparib) in 30 people with endometrial cancer that had come back or continued to grow after prior treatment. The goal was to see if the drug mix could shrink tumors or slow the cancer. The trial is c…

This study tested a combination of three drugs (afuresertib, sintilimab, and chemotherapy) in 22 adults with solid tumors like lung, cervical, or stomach cancer that had stopped responding to prior immunotherapy. The goal was to find the safest dose and see if the combo could shr…

This early-stage study tested a new drug called RP903 in 69 people with advanced solid tumors (like ovarian, breast, or cervical cancer) who had no other treatment options. The main goal was to check the drug's safety and find the right dose, not to cure the cancer. While some pa…

This study tested a high-dose internal radiation method called brachytherapy in 43 people with cervical, endometrial, esophageal, prostate, or biliary cancer. The goal was to see if the radiation implants could be placed accurately to deliver the right dose. Participants received…

This study looked at whether adding the drug aprepitant to the usual two anti-nausea medicines can better prevent nausea and vomiting caused by chemotherapy in people with gynecologic cancers like ovarian, cervical, and endometrial cancer. 143 patients took part. The goal was to …

This study looked at whether a 12-week program of aerobic and strength exercises could improve heart health and fitness in women who finished treatment for endometrial cancer. 33 survivors participated. The goal was to see if exercise helps blood vessels work better and reduces h…

This study tested a home-based brain training program for 60 women who had finished chemotherapy for gynecologic cancers (like ovarian or uterine cancer) and were experiencing memory or thinking problems. Participants used a computer program called BrainHQ for 10 weeks. The goal …

This study looked at a shorter, more intense radiation schedule for people with endometrial cancer after surgery. The goal was to see if it is safe and does not cause too many side effects. Eight participants were followed for three months to check for bladder and bowel issues an…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study looked at 150 women with intermediate- or high-risk endometrial cancer to compare two levels of lymph node removal during surgery: high versus low para-aortic lymphadenectomy. The goal was to see which approach gives better information about cancer spread and helps gui…

This study measured 14 different trace elements (like iron, selenium, and lead) in the blood of women with endometriosis, ovarian cancer, or endometrial cancer, and compared them to healthy women. The goal was to see if certain minerals are higher or lower in these conditions. Ea…

This study looked at whether high-intensity interval training (HIIT) before standard surgery could have anti-cancer effects in women with endometrial cancer. Thirty women participated, and researchers measured changes in tumor growth markers in tissue samples taken before and aft…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to use a mobile website, receive two motivational coaching calls, o…

This study tested a new follow-up approach for people who finished treatment for gynecologic cancers like ovarian, endometrial, cervical, or vulvar cancer. Instead of seeing a doctor every time, patients met with a nurse at every other visit and used a smartphone app to learn sel…

This study tested a special clinic for women who finished treatment for early-stage breast or gynecologic cancer. The clinic used online surveys to track symptoms and connect patients with nurses or dietitians when needed. The goal was to see if this approach is practical and hel…

This study looked at how well the drug T-DXd works compared to usual treatments for people with several types of advanced cancers that have high levels of a protein called HER2. Researchers used existing data from earlier trials and real-world medical records to compare outcomes.…

This study looked at how chemotherapy affects the overall quality of life in women treated for stage II or III endometrial cancer. Researchers surveyed 51 women at least two years after their treatment ended, using standard questionnaires to measure physical, emotional, and socia…

This study looked at 66 women having hysterectomy (removal of the uterus) to compare two surgical methods: traditional laparoscopic surgery and a newer vaginal approach called vNOTES. The goal was to see if vNOTES causes less pressure on the brain during the procedure. Researcher…

This study reviewed medical records of 509 adults in Taiwan with advanced endometrial, ovarian, or cervical cancer. Researchers wanted to find out how many of these cancers have high levels of a protein called HER2 (IHC 3+). This information could help doctors identify patients w…

This study tested a new method for injecting a green dye to help surgeons find lymph nodes during robotic surgery for early-stage endometrial cancer. The new method uses real-time imaging to guide the injection, aiming to find more lymph nodes on both sides of the pelvis. 80 pati…

This study followed 102 women with ovarian, fallopian tube, or endometrial cancer to see how standard chemotherapy (carboplatin and paclitaxel) changes their sense of taste, muscle mass, and nutrition. Researchers measured these effects before, during, and after six cycles of tre…