ENDOMETRIAL CANCER

This study tested a new combination drug (MK-4280A) to see if it could help people with certain advanced cancers. It involved 163 people with either a type of advanced skin cancer (cSCC) or a type of endometrial cancer that had spread or returned. The goal was to see if the drug …

This study aimed to find the safest dose for a shorter, more convenient radiation schedule given after surgery for endometrial (uterine) cancer. It involved 8 patients who had already had surgery and needed pelvic radiation to help prevent the cancer from returning. The main goal…

This study tested a new three-drug combination (afuresertib, sintilimab, and chemotherapy) for people with advanced solid tumors that had stopped responding to prior immunotherapy. The goal was to find a safe, effective dose and see if this combination could help control cancer g…

This first-in-human study tested a new oral drug called RP903 in people with advanced cancers that had stopped responding to standard treatments. The main goals were to find a safe dose and see how the body processes the drug. The study focused on specific cancers, including ovar…

This study tested a much shorter, 5-day course of radiation therapy for women with certain types of advanced uterine cancer who had already had a hysterectomy. Researchers wanted to see if this shorter treatment could control the cancer as well as the traditional 5-6 week course,…

This study tested whether a 12-week home exercise program could improve heart and blood vessel health in women who had finished treatment for early-stage endometrial cancer. Thirty-three participants received exercise equipment, a fitness tracker, and virtual coaching to follow a…

This study tested a combination of three existing drugs—bevacizumab, atezolizumab, and rucaparib—to see if they could work together to control recurrent or progressive endometrial cancer. It involved 30 patients whose cancer had returned or worsened after prior chemotherapy. The …

This study compared two different surgical approaches for removing lymph nodes in patients with intermediate or high-risk endometrial (uterine) cancer. Researchers wanted to see if removing lymph nodes higher up in the abdomen (high-level) was better than removing those lower dow…

This study tested a type of internal radiation treatment called high-dose-rate brachytherapy for several cancers, including cervical, prostate, and breast cancer. Researchers placed temporary radiation sources directly into or near tumors to deliver a strong, focused dose. The ma…

This study tested whether high-intensity interval training (HIIT) before standard surgery could slow the growth of endometrial cancer. Thirty women with early-stage endometrial cancer completed personalized HIIT workouts before their hysterectomy. Researchers measured changes in …

This early-stage study aimed to find a safe and effective dose of a new drug called TPST-1495, given alone or with an existing immunotherapy (pembrolizumab), for people with advanced solid tumors. It enrolled 89 adults with cancers like colorectal, lung, and head and neck cancer …

This study compared two ways to find 'sentinel' lymph nodes during robotic surgery for early-stage endometrial cancer. Surgeons tested a new method where they kept injecting a fluorescent dye until they could see the lymph channels light up in real-time. The goal was to see if th…

This study tested whether a new survivorship clinic could help women manage symptoms and improve quality of life after completing treatment for early-stage breast or gynecologic cancer. Researchers enrolled 200 women who had finished their primary cancer therapy within the past y…

This study aimed to find the best way to prevent severe nausea and vomiting caused by a common chemotherapy regimen for gynecologic cancers like ovarian and cervical cancer. Researchers tested whether adding a drug called aprepitant to the standard two-drug anti-nausea treatment …

This study looked at how chemotherapy affects the long-term quality of life for women treated for stage II or III endometrial cancer. Researchers compared 51 women who received chemotherapy plus radiation to those who received only radiation after surgery. The goal was to underst…

This study tested two new methods to encourage people at higher risk for hereditary cancers to get recommended genetic testing. Over 800 participants in Michigan were randomly assigned to either use a special website, receive two coaching phone calls, or get standard information.…

This study tested a digital tool designed to help cancer survivors learn about and decide whether to get genetic testing for hereditary cancer risk. Researchers wanted to see if this smart technology was easy to use and if it encouraged more people to get tested. They compared th…

This study compared two different surgical approaches for removing the uterus (hysterectomy) to see if one causes fewer pressure-related complications. Researchers measured pressure changes in the head during surgery in 66 women undergoing either a standard laparoscopic procedure…

This study aims to understand how common a specific protein marker called HER2 is in recurrent advanced endometrial, ovarian, and cervical cancers in Taiwan. Researchers will look back at the medical records and tissue samples of about 509 patients to see how many have high level…

This study aimed to understand if levels of various minerals and metals in the blood differ between healthy women and those with endometriosis, ovarian cancer, or endometrial cancer. Researchers compared blood samples from 40 women to look for patterns. The goal was to gather kno…

This study observed 102 women with ovarian, fallopian tube, or endometrial cancer to understand how standard chemotherapy affects their sense of taste, muscle mass, and nutrition. Patients were assessed before, during, and after six cycles of treatment. The goal was to gather inf…