Could a Low-Carb diet help fight endometrial cancer?

NCT ID NCT03285152

Completed Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study looks at whether a ketogenic diet—a very low-carbohydrate diet that forces the body to burn fat for energy—is safe and tolerable for overweight or obese women with newly diagnosed endometrial cancer before they have surgery. Nineteen participants will either follow the special diet or receive standard dietary counseling. The main goal is to see how many patients can complete the diet, not to measure cancer outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ketogenic diet
What this could lead to: If it works, this could point toward a dietary approach to help manage endometrial cancer before surgery.
What could go wrong: This is a very small, early feasibility study with only 19 participants, so results may not apply to everyone. The diet may be hard to follow or cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Consent and Follow up)

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Consent and Follow up)

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center @ Commack (Consent and Follow up)

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth (Consent and follow-up only)

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Consent and Follow-up)

Rockville Centre, New York, 11570, United States
Memorial Sloan Kettering Westchester (Consent & Follow Up)

Harrison, New York, 10604, United States
New York Weill Cornell Cancer Center at Cornell University

New York, New York, 10021, United States

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