New shorter radiation regimen tested for endometrial cancer

NCT ID NCT04458402

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase I study tested a shorter course of pelvic radiation (hypofractionated WPRT) in 8 patients with endometrial cancer after surgery. The goal was to see if this condensed schedule is safe and tolerable, focusing on side effects like bowel and bladder issues. The study is complete, but results are not yet reported.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiation therapy (hypofractionated whole pelvis radiation therapy)

What this could lead to

If successful, this could lead to a shorter, more convenient radiation schedule for endometrial cancer patients after surgery, with similar safety.

What could go wrong

This is a very small, early-phase study (only 8 participants) focused on safety, not effectiveness. The shorter radiation course may still cause significant side effects or may not control the cancer as well as standard treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ENDOMETRIAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Cincinnati Medical Center

    Cincinnati, Ohio, 45219, United States