New shorter radiation regimen tested for endometrial cancer

NCT ID NCT04458402

Completed Disease control Sponsor: Teresa Meier Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase I study tested a shorter course of pelvic radiation (hypofractionated WPRT) in 8 patients with endometrial cancer after surgery. The goal was to see if this condensed schedule is safe and tolerable, focusing on side effects like bowel and bladder issues. The study is complete, but results are not yet reported.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (hypofractionated whole pelvis radiation therapy)
What this could lead to: If successful, this could lead to a shorter, more convenient radiation schedule for endometrial cancer patients after surgery, with similar safety.
What could go wrong: This is a very small, early-phase study (only 8 participants) focused on safety, not effectiveness. The shorter radiation course may still cause significant side effects or may not control the cancer as well as standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER

Contacts and locations

Locations

University of Cincinnati Medical Center

Cincinnati, Ohio, 45219, United States

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