Triple-Drug cocktail shows promise for tough uterine cancer

NCT ID NCT01797523

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 31 times

Summary

This study tested whether a combination of three drugs—everolimus, letrozole, and metformin—can help control advanced or recurrent endometrial cancer. The 62 participants had cancer that had come back or spread and had limited prior treatments. The goal was to see how many patients had their cancer shrink or stop growing, and to check the safety of the drug combination.

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Contacts and locations

Locations

  • Lyndon B Johnson General Hospital

    Houston, Texas, 77026, United States

  • MD Anderson Cooper Cancer Center

    Voorhees Township, New Jersey, 08043, United States

  • Memorial City Medical Center

    Houston, Texas, 77024, United States

  • Sacred Heart Health Systems

    Pensacola, Florida, 32504, United States

  • The Woman's Hospital of Texas

    Houston, Texas, 77054, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.