Exercise before surgery may slow cancer growth

NCT ID NCT04025229

Completed Knowledge-focused Sponsor: UNC Lineberger Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether high-intensity interval training (HIIT) — short, intense exercise sessions — could have anti-cancer effects in women with endometrial cancer. Thirty women did 4 to 6 HIIT sessions before their scheduled surgery. Researchers then checked tissue samples for changes in a marker called Ki-67, which indicates how fast cancer cells are growing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-intensity interval training (HIIT) exercise
What this could lead to: If this works, it could point toward exercise as a way to slow tumor growth before surgery for endometrial cancer.
What could go wrong: This is a very small, early study with only 30 participants and no comparison group, so results may not be reliable or apply to others.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER

Contacts and locations

Locations

UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States

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