New dye technique may help surgeons spot hidden cancer spread

NCT ID NCT05191212

Completed Knowledge-focused Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a modified method for injecting a green dye (indocyanine green) to help surgeons see lymph nodes during robotic surgery for early-stage endometrial cancer. The new approach injects the dye until the lymphatic channels are visible in real time, aiming to improve detection of sentinel lymph nodes on both sides of the pelvis. The trial enrolled 80 patients and compared this technique with the standard injection method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: indocyanine green (ICG)
What this could lead to: If the modified technique proves better, it could improve the accuracy of sentinel lymph node detection during surgery for early-stage endometrial cancer.
What could go wrong: This is a small, single-center study with 80 participants, so results may not apply broadly. The intervention is a procedural variation, not a new drug or cure.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm uterine cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER ENDOMETRIAL NEOPLASMS SENTINEL LYMPH NODE BIOPSY (SLNB)

Contacts and locations

Locations

Gökhan Demirayak

Istanbul, 34147, Turkey (Türkiye)

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