DIABETES MELLITUS, TYPE 1

This study is testing whether adding mental health support to regular diabetes care helps adults with type 1 diabetes. Participants will complete surveys about their mood and health habits every six months. Some will also work with a mental health coach by phone or video to set p…

This study is testing a 6-month family coaching program to see if it can help manage weight and improve health in young people with type 1 diabetes who are also overweight or obese. The program includes both the child and at least one overweight parent, using a mix of in-person a…

This study is testing whether providing a continuous glucose monitor and a dedicated Patient Navigator can help people with type 1 diabetes who have struggled with severe complications or high blood sugar. It aims to see if this combination of technology and personal support impr…

This study is testing whether two oral medications can help preserve the body's remaining ability to produce insulin in people recently diagnosed with type 1 diabetes. It involves 78 participants aged 12-35 who were diagnosed within the last 100 days. Participants will take one o…

This study is testing if using a continuous glucose monitor (CGM) can help diabetic patients on kidney dialysis manage their blood sugar better than the standard method of finger-prick checks. It will involve 96 participants who will be assigned to either use a CGM continuously, …

This is an early safety study testing a new device called ENC-201-CED. It is designed to protect insulin-producing cells (islets) after they are transplanted under the skin in people with Type 1 diabetes. The main goal is to see if the device is safe and well-tolerated in 10 part…

This study is testing if a medication called dulaglutide can improve the health of tiny blood vessels in the muscles of adults with type 1 diabetes. Researchers believe better blood flow might help the body use insulin more effectively. The trial is currently suspended and was co…

This study follows children and teenagers who recently received a drug called teplizumab for type 1 diabetes. The goal is to monitor their health for any long-term side effects over the next 3.5 years. No new treatment is given; researchers are just observing participants who fin…

This study is testing the safety of transplanting insulin-producing cells from donors into adults with severe, unstable type 1 diabetes. The goal is to see if this procedure can help control blood sugar levels, reduce or eliminate the need for insulin injections, and prevent dang…

This study is testing the safety and how the body processes teplizumab in very young children (under 8 years old) who have early signs of type 1 diabetes but haven't developed full symptoms yet. About 20 children will receive the drug through daily IV infusions for 14 days, and r…

This early-stage study aimed to test the safety and effectiveness of implanting clusters of pancreatic cells (SR-02) into the abdomen of adults with Type 1 diabetes who experience severe low blood sugar. The goal was to see if the implanted cells could help the body produce its o…

This study is testing a new 6-month peer mentorship program designed to help teenagers with type 1 diabetes use their continuous glucose monitors (CGMs) more regularly. It compares the program, which includes monthly meetings with a mentor family and a health coach, to standard m…

This study aimed to test whether a combination of four drugs could help people recently diagnosed with type 1 diabetes keep making their own insulin. The goal was to see if this treatment could protect the body's remaining insulin-producing cells better than a placebo. The trial …

This study is testing if adding the common diabetes medication metformin to usual care can help prevent dangerous high blood pressure disorders during pregnancy in women with type 1 diabetes. Researchers are enrolling 60 pregnant women with type 1 diabetes to take either metformi…

This study is collecting feedback from people already using the DuraTouch insulin injection device in their daily lives. About 125 people with type 1 or type 2 diabetes will rate how easy, convenient, and satisfying the device is to use over 12 weeks. The goal is to understand th…

This study aims to understand how people with type 1 diabetes experience aging compared to people without the condition. Researchers will observe 400 participants over 65 years old to measure their physical, mental, and overall health. The goal is to identify what factors help pe…