DIABETES MELLITUS TYPE 1

This study looked at how aerobic and resistance exercise impact blood sugar levels after meals in children and teens (ages 10-18) with type 1 diabetes. The goal was to find which type of exercise helps control blood sugar spikes after eating. The study included 49 participants wh…

This study looked at how quickly a new fast-acting insulin (faster aspart) enters the blood compared to a standard insulin (NovoRapid) in 23 Chinese adults with type 1 or type 2 diabetes. Each participant received one injection of each insulin on separate visits, and blood sample…

This study tested a new system called Tandem Freedom in 10 adults with type 1 diabetes who already use Control-IQ technology. Participants used their usual system at home for a week, then switched to Tandem Freedom during a supervised hotel stay. The goal was to check safety by c…

This study tested whether taking high doses of omega-3 fatty acids (fish oil) and vitamin D is safe and can help people with type 1 diabetes keep making some of their own insulin. It included 27 people aged 6 to 65, both newly diagnosed and those living with diabetes for up to 10…

This study tested whether the Omnipod 5 system, a wearable insulin pump that automatically adjusts insulin, works better than multiple daily insulin injections for managing type 1 diabetes. 189 children and adults aged 4 to 70 took part. The main goal was to see if the pump impro…

This study looked at how safe and effective Fiasp® insulin is for people with type 1 or type 2 diabetes. It involved 42 adults who used the insulin as their doctor prescribed. The study lasted about 6 months and tracked side effects and blood sugar control.

This early-stage study tested a new medicine, NNC0363-1063, in 117 healthy volunteers and people with type 1 diabetes. The goal was to check safety, how the body processes the drug, and its effect on blood sugar. This is not a cure; it aims to help control diabetes with ongoing t…

This study tested a computer system that uses continuous glucose monitor data to give personalized advice to adults with type 1 diabetes. The goal was to see if this system helps control blood sugar better than standard sensor-augmented pump therapy. Researchers also looked at ho…

This study tested a program to help teens and young adults (ages 16-25) with type 1 diabetes improve their blood sugar control. The program focused on supporting their independence and motivation to manage their diabetes. 113 participants took part, and the goal was to see if thi…

This study tested two different methods for calculating insulin doses before meals in 76 children with type 1 diabetes. The goal was to see which method leads to better blood sugar control after eating. All children used an insulin pump and had diabetes for over a year. The resul…

This study tested a new insulin called icodec that is injected just once a week, compared to a standard daily insulin (degludec), in 582 adults with type 1 diabetes. Both groups also used mealtime insulin. The goal was to see if the weekly insulin controls blood sugar as well as …

This early-stage trial tested whether a new drug called R-5280 is safe and tolerable for children aged 11 to 17 who were recently diagnosed with type 1 diabetes. Nine participants received the drug or a placebo, and researchers monitored side effects, blood sugar levels, and gut …

This study tested a new insulin delivery system called Tandem Freedom in 10 adults with type 1 diabetes. Participants used their usual system at home for a week, then switched to the new system in a supervised hotel setting. The goal was to check safety by monitoring for severe l…

This study tested a new medicine called dasiglucagon against the standard treatment glucagon for severe low blood sugar in Asian adults and Japanese teenagers with type 1 diabetes. The goal was to see if dasiglucagon raises blood sugar just as quickly and safely. Participants rec…

This study tested whether real-time remote continuous glucose monitoring (CGM) and secure text messaging could improve blood sugar control in 20 adolescents (ages 13-18) with poorly controlled type 1 diabetes. Participants wore a CGM that shared their glucose levels with the stud…

This study tested whether combining two immune therapies—abatacept (injected weekly) and nasal insulin (sprayed into the nose)—can help preserve the pancreas's ability to make insulin in people recently diagnosed with type 1 diabetes. 68 participants aged 6 to 21 took part for 48…

This study tested a new fast-acting insulin (faster aspart) against a standard insulin (NovoRapid) in 331 adults with type 1 or type 2 diabetes. Both insulins were taken alongside a long-acting insulin, with or without metformin. The goal was to see if the new insulin works bette…

This study tested whether personalized text messages can help young adults with type 1 diabetes feel more confident managing their condition as they move from pediatric to adult care. 234 participants received either usual care or usual care plus text message support. The goal wa…

This study tested an automated insulin delivery system (a smart pump) in 15 adults with type 1 or type 2 diabetes who also have advanced kidney disease or are on dialysis. Participants used the system for 8 weeks, then switched to their usual care for another 8 weeks. The goal wa…

This study tested a fully automated system that delivers both insulin and glucagon to manage blood sugar in adults with type 1 diabetes. Over 12 months, 243 participants used the dual-hormone closed loop system or standard care. The goal was to see if the system helps people spen…

This study tested whether a newer insulin (glargine) is safer and better at controlling blood sugar than older human insulin in young people aged 7-25 with type 1 diabetes living in low-resource settings. 400 participants were randomly assigned to receive either glargine or stand…

This study tested a smart insulin pen system (Smart MDI) against standard daily injections in 179 people with type 1 diabetes. The goal was to see if the smart system helps keep blood sugar in a healthy range more consistently. Participants used either the smart pen with continuo…

This early study tested a new treatment called Stem Cell Educator therapy in 13 adults with type 1 diabetes. The therapy uses a device to 'educate' the patient's own immune cells outside the body, aiming to calm the immune attack on the pancreas. The main goals were to check safe…

This study tested whether using a continuous glucose monitor (CGM) in the hospital can help keep blood sugar levels in a safe range for people with type 1 or high-risk type 2 diabetes. 157 patients wore a wireless CGM that sent real-time glucose readings to a care team, who then …

This study tested a new fast-acting insulin (NNC0471-0119) given through an insulin pump in 43 adults with type 1 diabetes. Researchers measured how quickly the insulin entered the bloodstream and lowered blood sugar, comparing it to a standard insulin (insulin aspart). The goal …

This study looked at whether using a smart insulin pen (NovoPen 6) with two insulins (Tresiba and Fiasp) helps people with type 1 diabetes achieve better blood sugar levels. Over 400 adults used the pen for about 9-11 months, tracking their doses and glucose data via a mobile app…

This study tested whether a 6-month online mindfulness program could help adults with uncontrolled type 1 or type 2 diabetes lower their blood sugar. Over 300 participants were randomly assigned to either mindfulness training or a stress management education class. The main goal …

This study looked at how easy and convenient the DuraTouch® device is for people with type 1 or type 2 diabetes. 128 participants used the device for about 12 weeks and rated their satisfaction. The goal was to see if the device makes diabetes management simpler and more convenie…

This study looked at whether viruses in pregnant women with diabetes might increase the risk of congenital heart defects in their babies. Researchers analyzed blood and stool samples from 114 women to detect enteroviruses and other viruses. The goal was to gather knowledge for fu…

This study looked at how often sleep apnea occurs in adults with type 1 diabetes. Researchers monitored 53 participants overnight using sleep tests and continuous glucose monitors. The goal was to find out if sleep apnea is common in this group and whether it affects blood sugar …

This study tested a new smartphone-based tool called PEPPER that gives personalized insulin dose advice to people with Type 1 Diabetes. The tool uses artificial intelligence to learn from each person's past data and includes safety alarms for low blood sugar. Eight adults used th…

This study aims to better understand and diagnose insulin allergy, a rare but serious condition in people with diabetes who need insulin to live. Researchers will test a step-by-step method to identify the exact cause of the allergy and study the immune system's role. The goal is…

This study followed 87 active adults with type 1 diabetes who use automated insulin delivery systems and exercise at least twice a week. Researchers tracked their blood sugar levels before, during, and after exercise to see how well the technology helps control glucose in real-li…

This study looked at whether lowering insulin doses with a low-carb diet could improve how the body responds to insulin and blood vessel health in people with type 1 diabetes. Fourteen adults on insulin pumps tried both a low-carb and a standard diet for one week each. Results sh…

This study tested whether having a Diabetes Navigator—a guide who provides extra support—helps people with type 1 diabetes improve their use of advanced devices like continuous glucose monitors and insulin pumps. 148 participants were split into two groups: one received standard …

This study looked at how different types of exercise (short bursts vs. steady moderate activity) and timing (before or after meals) affect blood sugar in 21 active adults with type 1 diabetes. Participants did four cycling sessions while their glucose was tracked. The goal was to…