DIABETES MELLITUS TYPE 1

This study tested a new automated insulin delivery system for people with diabetes who also have advanced kidney disease or are on dialysis. The goal was to see if this 'artificial pancreas' system could better control blood sugar levels compared to usual care. Fifteen participan…

This study tested if a smart continuous glucose monitor (CGM) system could better manage type 1 diabetes than standard sensor-augmented therapy. Researchers wanted to see if customizing the system's advice based on a person's psychological and behavioral traits could improve bloo…

This study aimed to find out if a newer, more expensive type of insulin (glargine) works better than older, cheaper human insulin for young people with type 1 diabetes in low-resource settings. It involved 400 participants aged 7-25 and measured how well each insulin controlled b…

This study tested whether using a wireless continuous glucose monitor (CGM) could help hospital staff better manage blood sugar for patients with type 1 or high-risk type 2 diabetes. The CGM sent real-time data to a specialized nurse who worked with the care team to try to keep p…

This study tested a new, faster-acting insulin (faster aspart) against a standard insulin (NovoRapid®) in adults with type 1 or type 2 diabetes. Over 300 participants took four daily injections of one of the insulins, combined with a long-acting insulin, for about 7 months. The m…

This study tested a new 'Smart MDI' system, which includes a smart insulin pen and a glucose sensor, to see if it helps people with type 1 diabetes manage their blood sugar as well as or better than their usual insulin injections and sensor. About 179 adults and children used eit…

This study tested a new long-acting insulin (icodec) that is injected just once a week against a standard daily insulin (degludec) in adults with type 1 diabetes. The goal was to see if the weekly insulin could control blood sugar levels just as effectively and safely over 26 wee…

This study tested whether combining two immune-modifying treatments—abatacept (a weekly injection) and nasal insulin (a spray)—could help protect the pancreas's remaining insulin-producing cells in children and young adults recently diagnosed with type 1 diabetes. The goal was to…

This small study tested the safety of a new automated insulin delivery system called Tandem Freedom for adults with type 1 diabetes. Ten participants who already used a similar system tried the new device for two days in a supervised hotel. Researchers checked for dangerous low o…

This small, early-stage study tested the safety and side effects of a new oral treatment called R-5280 in teenagers recently diagnosed with Type 1 diabetes. For 12 weeks, participants took either the treatment or a placebo pill. Researchers checked for side effects and also measu…

This small study tested the safety of a new automated insulin delivery system called Tandem Freedom. Ten adults with type 1 diabetes used the system for four nights in a supervised hotel setting. The main goal was to check for dangerous low or high blood sugar events while the sy…

This small, early-stage study tested whether taking high doses of omega-3 fatty acids and vitamin D is safe and might help people with type 1 diabetes. The goal was to see if these supplements could protect the body's remaining insulin-producing cells, potentially slowing the dis…

This study looked at whether a smart insulin pen could help adults with Type 1 diabetes better manage their blood sugar levels. Over 400 participants used the NovoPen 6, which records insulin doses and sends the data to a phone app alongside their continuous glucose monitor readi…

This study tested whether a 6-month online mindfulness course could help adults with uncontrolled type 1 or type 2 diabetes better manage their blood sugar levels. Researchers compared the mindfulness program to a standard stress management education course, with both delivered i…

This study tested if having doctors remotely monitor teens' continuous blood sugar data in real-time could help improve their diabetes control. Twenty teenagers with poorly managed type 1 diabetes wore a sensor that sent glucose readings to the study team via smartphone for three…

This study tested whether having a 'Diabetes Navigator'—a support person who helps patients overcome challenges—was better than standard care at helping people with type 1 diabetes start using or improve their use of advanced technology like continuous glucose monitors and insuli…

This study aimed to find out which of two different methods for calculating insulin doses works better for controlling blood sugar after meals in children with type 1 diabetes. Researchers enrolled 76 children who had been using an insulin pump for at least three months. They com…

This study tested a new, fast-acting insulin designed for use in insulin pumps by people with type 1 diabetes. Researchers compared how quickly and effectively this new insulin (NNC0471-0119) lowers blood sugar compared to a commonly used insulin (aspart). The study involved 43 a…

This study looked at whether high-intensity interval training (HIIT) or moderate continuous exercise is better for managing blood sugar in adults with type 1 diabetes, and if exercising before or after a meal makes a difference. Twenty-one physically active adults completed four …

This study tested a new behavioral support program designed to help teens and young adults (ages 16-25) with Type 1 diabetes improve their daily self-care and lower their long-term blood sugar levels. The program used tools like text message reminders, motivational coaching, and …

This 12-month study tested a new automated system that delivers both insulin and glucagon to manage type 1 diabetes. It involved 243 adults in the Netherlands and compared this dual-hormone system to their current standard or advanced care. The main goal was to see if the new sys…

This study tested whether a new emergency medication called dasiglucagon works as well as the standard glucagon treatment for quickly raising dangerously low blood sugar in people with type 1 diabetes. The trial involved 38 Asian adults and Japanese adolescents who received both …

This study aimed to better understand and diagnose insulin allergies, a rare but serious problem where a person's body reacts badly to the insulin they need to manage diabetes. Researchers worked with 55 adults who had diabetes—some with insulin allergies and some without—to test…

This small, completed study aimed to understand if reducing insulin doses by following a low-carbohydrate diet could improve how the body uses insulin and the health of blood vessels in people with type 1 diabetes. It involved 14 adults who tried both a low-carb and a standard di…

This study aimed to understand how different types of exercise affect blood sugar levels after a meal in children and teens with type 1 diabetes. Researchers compared 30 minutes of brisk walking (aerobic) to 30 minutes of resistance band exercises, both done after a standardized …

This study aimed to find out how common obstructive sleep apnea is in adults with Type 1 diabetes. Researchers monitored 53 participants overnight in a hospital to check their breathing and blood sugar levels. The goal was to gather information, not to test a new treatment.

This research study aimed to understand if viruses in pregnant women, especially those with diabetes, might increase the risk of heart defects in their babies. Researchers analyzed blood and stool samples from 114 women to look for viruses and the body's immune response to them. …

This study observed how automated insulin pumps manage blood sugar in active adults with type 1 diabetes during their regular exercise routines. It followed 87 people in France for one month, tracking their glucose levels before, during, and after workouts. The goal was to gather…

This study measured how quickly a new, faster-acting insulin gets into the bloodstream compared to a standard insulin. It involved 23 Chinese adults with type 1 or type 2 diabetes. Each participant received one injection of each insulin type, and researchers took frequent blood s…