Can fish oil and vitamin d help preserve insulin in type 1 diabetes?

NCT ID NCT03406897

Completed Disease control Sponsor: Rodolfo Alejandro Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether high doses of omega-3 fatty acids (fish oil) and vitamin D are safe and can help preserve insulin production in people with type 1 diabetes. The trial included 27 participants, both children and adults, who had diabetes for up to 10 years. Researchers measured changes in C-peptide (a marker of insulin production) and blood sugar control over one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Omega-3 fatty acids and vitamin D (cholecalciferol)
What this could lead to: If it works, this could point toward a simple supplement approach to help preserve insulin production in people with type 1 diabetes.
What could go wrong: This is a small, early-phase pilot trial with only 27 participants, so results may not apply widely. High doses of supplements can also have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus hypoglycemia type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS DIABETES MELLITUS, TYPE 1 DIABETES, AUTOIMMUNE HYPOGLYCEMIA

Contacts and locations

Locations

Diabetes Research Institute, University of Miami Miller School of Medicine

Miami, Florida, 33136, United States

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