Could a tiny device free people with type 1 diabetes from daily shots?

NCT ID NCT06408311

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a small device placed under the skin that contains insulin-producing cells. The goal is to see if it is safe and tolerable for people with type 1 diabetes who already receive standard islet transplants. Only 10 participants are enrolled, and the main focus is on safety, not yet on how well it controls blood sugar.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

macro-encapsulated human primary islets

What this could lead to

If successful, this could lead to a safer way to transplant insulin-producing cells without lifelong immune suppression, potentially improving blood sugar control.

What could go wrong

This is a very early Phase 1 trial with only 10 participants, so safety and feasibility are the main goals. The device may not work as hoped, and long-term benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McGill University Health Centre

    Montreal, Quebec, H4A 3J1, Canada

  • UHN

    Toronto, Ontario, M5G 2C4, Canada