Could stem cells help newly diagnosed type 1 diabetes patients?

NCT ID NCT04061746

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests whether a single infusion of umbilical cord stem cells can safely preserve insulin production in adults newly diagnosed with type 1 diabetes. Sixty participants will receive either the stem cells or a placebo. The main goal is to see if the treatment protects the cells that make insulin, potentially reducing the need for insulin injections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

umbilical cord-derived mesenchymal stem cells (MSCs)

What this could lead to

If it works, this could help people with new-onset type 1 diabetes keep making some of their own insulin, reducing the need for daily insulin shots.

What could go wrong

This is an early Phase 1 trial focused on safety, so it is not yet proven to work. The effects may be small or temporary, and there are risks from the infusion itself.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States