Islet cell transplant aims to free diabetics from insulin shots

NCT ID NCT00160732

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests if transplanting donor islet cells into the liver can safely help people with difficult-to-control type 1 diabetes achieve normal blood sugar levels without insulin. Up to 50 adults aged 18-58 who have had diabetes for at least 5 years and still struggle with blood sugar swings despite intensive insulin therapy will receive the cells along with anti-rejection drugs. The goal is to reduce or eliminate the need for insulin injections, but lifelong immunosuppression is required.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Chicago Hospitals

    Chicago, Illinois, 60637, United States