Brain scans reveal why some diabetics miss danger signs

NCT ID NCT04387422

Ongoing Knowledge-focused Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses brain imaging to understand why some people with type 1 diabetes lose their ability to sense dangerously low blood sugar. Researchers will temporarily induce low blood sugar in participants and scan their brains to see how glucose levels change. The goal is to learn more about this condition, not to test a new drug or treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help explain why some people with type 1 diabetes stop feeling low blood sugar symptoms, potentially pointing toward ways to restore that awareness.
What could go wrong: This is a small, early-stage observational study with only 50 participants. It is not testing a treatment, so it may not lead directly to any new therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS, TYPE 1

Contacts and locations

Locations

University of Minnesota

Minneapolis, Minnesota, 55455, United States

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