Could a TB vaccine help kids with type 1 diabetes?
NCT ID NCT05180591
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving the BCG vaccine (traditionally used for tuberculosis) twice, four weeks apart, can help children aged 8 to 18 with type 1 diabetes. The goal is to see if it improves blood sugar control, reduces insulin use, and lowers the risk of dangerously low blood sugar. The trial is active but no longer recruiting new participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BCG vaccine (Bacillus Calmette-Guérin)
What this could lead to
If it works, this could offer a new way to help children with type 1 diabetes manage their blood sugar levels and reduce insulin needs.
What could go wrong
This is a mid-stage trial with 150 participants, so results are not yet proven. The BCG vaccine may not improve diabetes control, and side effects like injection-site reactions are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Immunobiology Labs CNY 149
Charlestown, Massachusetts, 02129, United States