New pill aims to slash severe hypoglycemia in type 1 diabetes

NCT ID NCT06334133

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tests an experimental pill called cadisegliatin taken alongside insulin in adults with type 1 diabetes. The goal is to see if it can lower the number of dangerously low blood sugar events (hypoglycemia) without worsening overall blood sugar control. About 150 participants will receive either the pill or a placebo for 26 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DIABETES MELLITUS, TYPE 1 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 310 Clinical Research

    Inglewood, California, 90301, United States

  • AMC Community Endocrinology

    Albany, New York, 12203, United States

  • AME Clinical Research

    Huntington Beach, California, 92647, United States

  • Accellacare - McFarland

    Ames, Iowa, 50010, United States

  • Acclaim Clinical Research

    San Diego, California, 92120, United States

  • Amicis Research Center

    Granada Hills, California, 91344, United States

  • Atlanta Diabetes Associates

    Atlanta, Georgia, 30318, United States

  • Baptist Health Center for Clinical Research

    Little Rock, Arkansas, 72205, United States

  • BayCare Health Systems

    Clearwater, Florida, 33756, United States

  • Centricity Research - Columbus

    Columbus, Georgia, 31904, United States

  • Centricity Research Morehead City Multispecialty

    Morehead City, North Carolina, 28557, United States

  • Circle Clinical Research

    Sioux Falls, South Dakota, 57104, United States

  • Citta Clinical Research, LLC

    Spokane, Washington, 99202, United States

  • Consano Clinical Research

    Shavano Park, Texas, 78231, United States

  • DM Clinical Research

    Indianapolis, Indiana, 46254, United States

  • Denver Endocrinology Diabetes and Thyroid Center

    Englewood, Colorado, 80113, United States

  • Diabetes & Endocrinology Associates of Stark County, Inc

    Canton, Ohio, 44718, United States

  • Diabetes & Glandular Disease Clinic, P.A.

    San Antonio, Texas, 78229, United States

  • Excel Clinical Research

    Las Vegas, Nevada, 89109, United States

  • Focus Clinical Research

    West Hills, California, 91307, United States

  • IMAX Clinical Trials

    La Palma, California, 90623, United States

  • Iowa Diabetes and Endocrinology Research Center

    West Des Moines, Iowa, 50265, United States

  • Jacobi Medical Center

    The Bronx, New York, 10461, United States

  • Javarra Inc.

    Charlotte, North Carolina, 28210, United States

  • John Muir Physician Network Clinical Research Center

    Concord, Ohio, 94520, United States

  • Johnson County Clin-Trials, LLC

    Lenexa, Kansas, 66219, United States

  • Massachusetts General Hospital Diabetes Research Center

    Boston, Massachusetts, 02114, United States

  • MedStar Good Samaritan Hospital

    Baltimore, Maryland, 21239, United States

  • Metabolic Research Institute, Inc

    West Palm Beach, Florida, 33413, United States

  • Palm Research Center

    Las Vegas, Nevada, 89128, United States

  • Paradigm Clinical Research

    Boise, Idaho, 83709, United States

  • Paradigm Clinical Research - Modesto

    Modesto, California, 95355, United States

  • Paradigm Clinical Research Centers LLC

    San Diego, California, 92108, United States

  • Physician's East PA

    Greenville, North Carolina, 27834, United States

  • Profound Research LLC

    Farmington Hills, Michigan, 48334, United States

  • SMS Clinical Research LLC

    Mesquite, Texas, 75149, United States

  • Scottsdale Clinical Trials

    Scottsdale, Arizona, 85260, United States

  • Scripps Whittier Diabetes Institute

    La Jolla, California, 92037, United States

  • Solace Clinical Research

    San Juan, 00907, Puerto Rico

  • Southern Endocrinology Associates PA

    Mesquite, Texas, 75149, United States

  • Tekton Research, LLC

    McKinney, Texas, 75069, United States

  • Texas Diabetes and Endocrinology, P.A

    Austin, Texas, 78731, United States

  • The Jones Center Clinical Research, LLC

    Macon, Georgia, 31210, United States

  • The Lundquist Institute

    Torrance, California, 90502, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27514, United States

  • University of Pennsylvania Perelman Center for Advanced Medicine

    Philadelphia, Pennsylvania, 19104, United States

  • University of Washington Diabetes Institute

    Seattle, Washington, 98109, United States

  • Vector Clinical Trials

    Reno, Nevada, 89511, United States

  • Velocity Clinical Research

    Medford, Oregon, 97504, United States

  • Velocity Clinical Research - Dallas

    Dallas, Texas, 75230, United States

  • Velocity Clinical Research - Spokane

    Spokane, Washington, 99218, United States

  • Wasatch Clinical Research, LLC

    Salt Lake City, Utah, 84107, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.