CHRONIC KIDNEY DISEASES

This small, completed study tested if a clinical trial could be run remotely to find the best personalized drug plan for protecting the kidneys of people with type 2 diabetes. Twelve participants tried a drug called empagliflozin at home, and based on their kidney test results, s…

This study tested whether a monthly injection called Ziltivekimab could reduce harmful inflammation in people with advanced chronic kidney disease. Researchers enrolled 264 adults with kidney disease and high inflammation levels to compare three different doses of the injection a…

This study tested whether an electronic alert system could help primary care doctors better identify and manage patients with chronic kidney disease (CKD). The system automatically flagged patients at risk and provided doctors with guideline-based advice. Researchers compared out…

This study tested whether a personalized educational worksheet and follow-up phone coaching could help people with chronic kidney disease (CKD) better manage their high blood pressure. 320 participants with moderate to severe CKD and uncontrolled blood pressure were assigned to r…

This study tested whether sending electronic reminder letters to patients with chronic kidney disease and their doctors could increase the use of recommended medications. Over 28,000 Danish adults with kidney disease were involved. Researchers wanted to see if these digital 'nudg…

This study tested whether pairing people with a community health worker for 10 months could help them better manage chronic health conditions like diabetes, high blood pressure, and obesity. The program provided navigation help to access health services, education, and support fo…

This study tested a new drug, TOUR006, designed to lower a key marker of inflammation (hs-CRP) in people with chronic kidney disease. Researchers wanted to see if giving the drug monthly or quarterly was safe and effective at reducing this inflammation. The goal is to see if cont…

This study tested whether a new drug called KBP-5074 could safely lower high blood pressure in people who also have moderate-to-severe chronic kidney disease. About 162 participants were randomly assigned to receive either one of two doses of the drug or a placebo pill for 84 day…

This study tested whether providing full hospital-level medical care in patients' own homes is a safe and effective alternative to traditional hospital stays for rural adults. It involved 160 adults with serious but manageable conditions like severe infections, heart failure, COP…

This study tested whether injections of a patient's own processed kidney cells (called REACT) could safely slow the worsening of kidney function in people with diabetes and chronic kidney disease. It involved 53 participants who received up to two injections into their kidneys an…

This study tested whether a digital support program could help people with chronic kidney disease and a care partner manage the condition better. Over 200 participants were split into two groups: one used the digital program alongside regular care, while the other received regula…

This study tested a new type of hemodialysis filter called ELISIO-HX. It aimed to check if the filter was safe for patients with kidney failure and if it could better remove certain waste products from the blood. The study involved 22 stable patients who were already on long-term…

This study tested whether a support program could help low-income African Americans with diabetic kidney disease who face challenges like food or housing insecurity. Fifty participants were randomly assigned to receive either the full program—which included education, help meetin…

This pilot study tested whether using a new type of blood pressure measurement, taken from the body's central arteries, is a better way to manage high blood pressure in people with advanced kidney disease. The goal was to see if this method is practical for doctors and patients t…

This study tested a medical device called the everlinQ System, which creates a connection between an artery and a vein for patients who need dialysis. The goal was to see if using a different vein location could make the procedure easier or more successful. Researchers followed 2…

This study tested whether training community health workers and doctors in trauma-informed care could improve life quality for people with advanced kidney disease in underserved urban neighborhoods. It focused on Black and Hispanic patients who often face barriers to the best kid…

This study tested a device called the everlinQ System, which is used to create a connection between an artery and a vein for patients who need regular dialysis due to kidney failure. The goal was to see if this less invasive method could successfully create a usable access point …

This study tested whether 3D ultrasound imaging could accurately measure the size of kidneys and kidney tumors. Researchers compared the 3D ultrasound measurements to the standard methods of CT and MRI scans in 53 adult patients. The goal was to see if this newer, often simpler i…

This study tested if new, non-invasive ultrasound scans could predict whether a surgically created dialysis access point would work properly. Researchers followed 76 patients with kidney failure, using special ultrasound techniques to measure blood vessel stiffness and function b…

This study tested whether a simple electronic alert in a doctor's computer system could help catch early kidney disease in people with type 2 diabetes. About 400 patients who had diabetes but hadn't had the recommended annual kidney check in the past year were included. The alert…

This small, completed pilot study tested whether a talk therapy program was acceptable and feasible for people with chronic kidney disease (CKD) who experience fatigue. Five participants took part in the program, which aimed to help manage fatigue through cognitive behavioral tec…

This study tested a new program designed to improve access to kidney transplants, especially for Black patients, by identifying eligible patients earlier and providing specialized support. Researchers compared this new outreach program to standard care to see if it helped more pe…

This study aimed to understand why women with chronic kidney disease have a higher risk of heart problems. Researchers compared blood vessel function and hormone levels in 51 women with kidney disease to healthy women. The goal was to see if changes in sex hormones, which protect…

This study tested whether a computer algorithm could predict when patients receiving hospital-level care at home might get sicker. Researchers used past patient data to train the algorithm and then checked how well it worked on a new group of over 500 patients. The goal was to se…

This study aimed to create a decision-making tool to help doctors identify which patients hospitalized with severe kidney injury are most likely to develop chronic kidney disease. Researchers followed 319 patients who needed dialysis for acute kidney injury to understand what fac…

This study looked back at medical records to see how well primary care doctors referred patients to kidney specialists using video calls. Researchers checked if referrals happened quickly enough and if patients were on the right medications before seeing the specialist. The goal …

This study looked back at medical records to understand how well a standard treatment works for patients with both sudden kidney failure and advanced liver disease, who also had signs of pre-existing chronic kidney problems. Researchers compared 490 hospitalized patients who rece…

This study looked back at past patient records to see if a computer program could learn to predict which patients are most likely to be readmitted to the hospital within 30 days after being sent home. Researchers used data from 372 patients who had been treated at home through a …

This study aimed to understand why people with chronic kidney disease often develop serious heart problems. Researchers used special heart scans (MRI) on 276 patients with kidney disease to look for patterns of heart damage, scarring, and swelling. The goal was to identify the sp…

This study aimed to understand why chronic kidney disease may progress faster in some people of African descent. Researchers looked at a specific gene called APOL1 in 88 adults from Guadeloupe with advanced kidney disease. They measured the gene's presence and checked for links t…

This study aimed to understand how the kidney medication dapagliflozin might work by looking at its effects on gut bacteria. Researchers observed 50 non-diabetic patients with chronic kidney disease who were starting this drug as part of their normal care. They checked if 12 week…

This study looked back at the health records of nearly 1 million Canadian adults to understand how the COVID-19 pandemic affected their regular care for long-term conditions like diabetes, heart failure, and depression. Researchers compared the number of doctor visits, tests, and…