CHRONIC KIDNEY DISEASES

This study looks at whether oral semaglutide, a drug already used for diabetes, can slow down kidney disease in people who also have fatty liver disease. About 90 adults with both conditions will receive either standard care plus semaglutide or standard care alone for two years. …

This study looks at whether empagliflozin, a diabetes medicine, can reduce protein leakage in urine for people with type 2 diabetes and very advanced chronic kidney disease (eGFR between 10 and 20). About 34 adults will take either empagliflozin or a placebo for 6 weeks each, and…

This study tests whether sending reminders to doctors can help more patients with chronic kidney disease get the right medications. About 1,000 adults with kidney disease will take part. The goal is to see if these alerts lead to better prescribing of treatments that can slow kid…

This study looks at whether starting four approved kidney medicines quickly (over about 8 weeks) is safe and works better than the usual step-by-step method in people with type 2 diabetes and chronic kidney disease. About 64 adults will be randomly assigned to either the rapid-st…

This study tests a new drug called QRX3 in 3000 people with chronic kidney disease (CKD) whose kidney function is declining. The goal is to see if QRX3 can improve kidney function and slow further damage. Participants will take the drug and have their kidney function measured ove…

This study will check if a new handheld device can accurately measure creatinine levels from a fingerstick at home, compared to standard lab tests. About 200 adults with kidney disease will use the device themselves and answer a questionnaire about how easy it is to use. The goal…

This study will test if doing virtual reality exercises during dialysis can help people with end-stage kidney disease keep their sodium, potassium, calcium, and phosphorus levels in a healthy range. About 40 adults on regular dialysis will take part. Researchers will measure mine…

This study will use advanced MRI scans to learn more about chronic kidney disease, kidney transplants, and how kidney problems may affect the brain. Researchers will scan 180 people, including healthy volunteers and those with kidney disease, to see if MRI can help track disease …

This study looks at a natural chemical called kynurenine in pregnant women with and without chronic kidney disease. Researchers want to see if low levels of this chemical are linked to preeclampsia, a serious condition that can harm mothers and babies. About 204 women will have t…

This observational study looks at how gum disease (periodontitis) and chronic kidney disease (CKD) may be connected through the 'oral-renal axis.' Researchers will study mouth and gut bacteria in 80 adults aged 18 to 75 to see if these microbes play a role. The goal is to better …

This study tests whether educational videos and text messages can help people with kidney failure learn about and pursue living-donor transplants. About 430 adults referred for a kidney transplant will be split into two groups: one gets the video-and-text program alone, the other…