New kidney pill aims to cut protein leak in diabetics

NCT ID NCT07667517

Not yet recruiting Disease control Sponsor: First Affiliated Hospital of Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug finerenone can reduce protein in the urine (a sign of kidney damage) in adults with type 2 diabetes and chronic kidney disease. About 148 participants will receive either finerenone or a placebo pill daily for 6 months, on top of their usual medications. The main goal is to see if more people on finerenone achieve a meaningful drop in urine protein levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: finerenone (a pill that blocks a hormone to protect the kidneys)
What this could lead to: If it works, finerenone could become a standard add-on treatment to help slow kidney damage and reduce protein leakage in people with diabetes.
What could go wrong: This is a Phase 4 trial with only 148 people, so results may not apply to everyone. Finerenone can raise potassium levels, which requires careful monitoring.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Albuminuria chronic kidney disease chronic renal failure syndrome proteinuria type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALBUMINURIA CHRONIC KIDNEY DISEASES TYPE 2 DIABETES MELLITUS (T2DM)

Contacts and locations

Locations

Fujian Provincial Hospital

Fuzhou, Fujian, China
Nanfang Hospital, Southern Medical University

Guangzhou, Guangdong, China
Nantong First People's Hospital

Nantong, Jiangsu, China
Sanshui Hospital, Zhujiang Hospital, Southern Medical University

Foshan, Guangdong, China
Shanghai Municipal Hospital of Traditional Chinese Medicine

Shanghai, Shanghai Municipality, China
Suzhou Science and Technology City Hospital

Suzhou, Jiangsu, China
The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Ningbo University

Ningbo, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China
The First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310003, China
The First People's Hospital of Suqian

Suqian, Jiangsu, China
Xi'an Daxing Hospital

Xi'an, Shaanxi, China
Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

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