CHRONIC KIDNEY DISEASES

This study is testing a medical device procedure called renal denervation for people whose high blood pressure remains uncontrolled despite medications. The procedure uses a catheter to deliver energy to nerves around the kidney arteries, aiming to lower blood pressure long-term.…

This study is testing a new way to care for older adults who receive dialysis. It adds a specialized geriatric team to the dialysis clinic to help manage common problems like memory issues, falls, and medication side effects. The goal is to see if this integrated approach is prac…

This early-stage study is testing if adding the drug belumosudil to a special kidney and stem cell transplant procedure can help patients safely stop taking lifelong anti-rejection medications. The goal is to see if the body can learn to accept the new kidney without needing cons…

This study is testing a lifestyle coaching program designed to help people with both metabolic syndrome and chronic kidney disease. The program focuses on improving diet and physical activity. Researchers want to see if this coaching can reduce waist size and help preserve kidney…

This early-stage study is testing a new drug called DISC-0974 in people with chronic kidney disease who also have anemia (low red blood cells). The main goal is to check if the drug is safe and how the body handles it. About 50 participants will receive either the experimental dr…

This large, late-stage trial is testing whether a low dose of the blood-thinning drug rivaroxaban can safely reduce the risk of heart attacks, strokes, and death in people with advanced or dialysis-dependent kidney disease. It will enroll 2,000 participants worldwide who have kid…

This study is testing whether a short, two-day course of a compound called fisetin can help people with advanced chronic kidney disease. Researchers want to see if fisetin can reduce body-wide inflammation, improve the function of certain repair cells, and help with physical stre…

This study is testing a new online health platform designed to help people receiving hemodialysis. The platform provides education and support for exercise, nutrition, and mental well-being. Researchers want to see if using this holistic, virtual program can improve patients' phy…

This study aims to understand why people with chronic kidney disease (CKD) often develop memory loss and thinking problems. Researchers are following 600 people, with and without CKD, for up to five years, tracking their cognitive function and taking brain scans. The goal is to i…

This study aims to understand how chronic kidney disease affects muscle mass and strength over time. Researchers will follow 80 people with kidney disease and healthy volunteers for one year, measuring their body composition and kidney function at two visits. The goal is to ident…

This study is creating a large registry to track the health of over 5,000 people in China with chronic kidney disease (CKD). It aims to collect detailed information on how the disease is currently diagnosed and treated, identify where care might fall short of guidelines, and find…

This study aims to collect information on how a specialized dialysis machine (CARPEDIEM) works for critically ill infants with severe kidney problems. Researchers will observe about 1000 infants across multiple hospitals who are already receiving this treatment as part of their s…

This study is testing whether a special ultrasound technique can create detailed pictures of tiny blood vessels in the kidneys. Researchers want to see if this imaging method works better than current approaches for understanding chronic kidney disease. The study includes both he…

This study is testing whether a special type of heart scan, called T1 mapping, can accurately detect heart disease and predict patient outcomes like survival and hospitalization. It will enroll 8,000 adults who are already scheduled for a heart scan for medical reasons. The goal …

This study is testing an educational tool designed to help people with chronic kidney disease make informed decisions about pregnancy and contraception. Kidney doctors will use this tool with 60 patients to see if it helps them feel better prepared for these important health choi…

This study aimed to test how different fluid volumes, dwell times, and glucose levels affect fluid removal during automated peritoneal dialysis. It planned to enroll kidney failure patients on stable dialysis to collect detailed treatment data. The goal was to improve the accurac…

This study aimed to develop a computer program that could predict how long patients would need to stay in home hospital care. Researchers used existing patient records to train the program, then tested it on different patient groups. The goal was to help hospitals better plan car…

This study aims to understand how genetics, lifestyle, and other factors influence the progression and severity of many common chronic diseases. Researchers will collect health records, genetic data, and samples from 120,000 participants with conditions like diabetes, arthritis, …

This study aims to understand how two different heart failure drugs affect the body's salt and fluid balance in people who have both heart failure and kidney disease. It will involve 60 participants who will try both drugs and a placebo in a random order. Researchers will closely…