CARDIOVASCULAR DISEASE

This study tested whether eating whole eggs helps older adults (ages 50-69) build more muscle when they do strength training. Researchers wanted to see if the cholesterol in eggs is important for muscle growth. They also checked if eating eggs raised participants' blood cholester…

This study tested whether a daily probiotic supplement could improve blood vessel function and reduce markers of inflammation in people with coronary artery disease or type 2 diabetes. Researchers enrolled 215 participants to see if changing gut bacteria could help control heart …

This study tested whether a special nurse-led program could help Veterans with HIV lower their blood pressure and reduce their risk of heart disease. The program involved 305 Veterans and combined care coordination, medication support, home blood pressure monitoring, and video ch…

This study tested whether a home-based rehabilitation program delivered through a smartphone app and regular phone calls could help veterans with heart or lung disease. The goal was to see if this convenient, remote approach could improve patients' fitness, help them manage their…

This early-stage study tested whether injecting donor stem cells into the leg muscles of patients about to have a major amputation could help prevent serious wound complications after surgery. The main goal was to check if the injections were safe. Researchers also wanted to see …

This was the first human study of an experimental drug called AMG 890 (now called olpasiran) designed to lower lipoprotein(a), a substance in blood linked to heart disease risk. Researchers tested single doses in about 80 adults with elevated lipoprotein(a) levels to check safety…

This study tested whether tildrakizumab, an FDA-approved drug for moderate-to-severe psoriasis, could improve how well the heart's tiny blood vessels work. Researchers enrolled 36 adults with psoriasis who also had risk factors for heart disease. They used heart imaging scans to …

This large study aimed to find out if taking daily cocoa extract (from cocoa beans) or a standard multivitamin could help prevent heart disease and cancer in older adults. Over 21,000 men aged 60+ and women aged 65+ were randomly assigned to take either the real supplements or pl…

This study tested a 9-week online therapy program designed to help people with heart disease manage stress, anxiety, and depression. 215 participants with stable heart conditions and emotional distress tried the flexible, personalized program. Researchers measured whether the onl…

This study aimed to understand how Mexican American families talk about their risk for common diseases like diabetes, heart disease, and cancer. Researchers worked with 498 adults from multigenerational households to see if sharing personalized risk information with the whole fam…

This study aimed to understand how skin and blood vessel flexibility are related in people with Williams syndrome, a genetic disorder that can cause heart and blood vessel problems. Researchers measured the stretchiness of skin and arteries in 43 participants, including people wi…

This study aimed to estimate how many adults in the United States might be eligible for a cholesterol-lowering drug called inclisiran. Researchers used national survey data to model the potential number of heart attacks, strokes, and other cardiovascular events that could be prev…

This study aimed to understand how different types of milk fat, altered by cow diets, affect cholesterol and other heart health markers. 107 healthy adults ate foods made with specific milk fats for four weeks while researchers tracked their blood cholesterol levels. The goal was…

This study aimed to understand the connection between physical activity and the risk of heart disease in women who have survived breast cancer. Researchers monitored 70 survivors for a week to measure their daily activity levels and exercise capacity. The goal was to gather evide…

This study aimed to see if newer psoriasis medications (IL17 or IL23 inhibitors) improve markers of artery stiffness and heart health over one year. It observed 66 patients with moderate-to-severe psoriasis who were already starting these treatments. The main goal was to measure …

This study looked at whether regularly getting 1.5 hours less sleep increases the risk of heart disease, weight gain, and diabetes in women. For 6 weeks at a time, 54 healthy women either slept their normal amount or had their sleep shortened. Researchers measured blood pressure,…

This study tested a process for telling veterans about genetic risks found in their health data, specifically for heart disease. Researchers compared giving this information immediately versus waiting six months to see if it changed how veterans managed their cholesterol. The goa…

This study aimed to understand why keeping weight off is so hard. After losing weight, 234 adults followed one of three diets with different amounts of carbs and fat, but the same protein. Researchers carefully measured how many calories their bodies burned and other health marke…

This long-term study aims to understand how having less elastic, stiffer blood vessels from birth affects different organs in people with Williams Syndrome or a related heart condition called SVAS. Researchers will observe up to 159 children and adults for up to 10 years, using s…

This study looked at whether a diagonal crease in the earlobe (called Frank's sign) is linked to smoking, a major risk for heart disease. Researchers examined 404 adults aged 40-59, comparing smokers and non-smokers. The goal was to see if this simple, non-invasive sign could hel…

This study aimed to understand how specific gene variations might affect blood vessel function, which is important for heart health. Researchers examined 178 healthy adults who carried certain gene patterns to see if these variations were linked to differences in how their blood …

This study aimed to better understand CADASIL, a rare and fatal genetic disease that causes strokes and dementia. Researchers observed 20 adults recently diagnosed with CADASIL over two years, performing various tests like brain scans, blood tests, and skin biopsies. The goal was…

This study aimed to learn how family members share health information when someone has a genetic-related disease like sickle cell, diabetes, or cancer. Over 1,000 adults who either had such a disease or were related to someone who did completed surveys about their family's health…

This study aimed to find better ways to detect early, hidden heart damage in people who survived childhood cancer after receiving certain chemotherapy drugs called anthracyclines. Researchers used advanced heart scans (MRI) and blood tests to look for subtle signs of heart proble…

This study aims to understand the long-term heart health and survival of people who donate a kidney. Researchers will compare health records of 50,000 living kidney donors in Canada to a carefully matched group of healthy people who did not donate. The goal is to see if donors ha…

This study aimed to understand how inflammation in rheumatoid arthritis affects heart disease risk. Researchers examined 74 adults with active rheumatoid arthritis who hadn't taken certain advanced medications. They measured blood flow to the heart to see if reducing inflammation…

This study aimed to understand if trans fats from natural sources like milk are different for heart health than trans fats from processed vegetable oils. Researchers had 46 healthy adults eat foods made with specially prepared fats from either milk or processed oils for several w…

This study aimed to understand how the chronic inflammation from psoriasis might increase a person's risk for heart disease and diabetes. Researchers followed 386 adults with psoriasis for up to 4 years, performing regular blood tests, heart scans, and optional skin biopsies. The…

This study aimed to understand the connection between inflammation and common health conditions like heart disease and diabetes. Researchers compared 150 adults with these conditions to healthy volunteers using blood tests, questionnaires, and special body scans. The goal was to …