Could a simple gas protect organs during surgery?

NCT ID NCT07638124

Completed Knowledge-focused Sponsor: Alexander Averyanov Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether giving inhaled nitric oxide gas during laparoscopic surgery could protect blood vessels and organs in 40 adults with heart disease. Half received the gas through their breathing tube during surgery, and half received standard care. Researchers measured markers of blood vessel health, kidney and gut injury, and recovery time to see if the gas had any protective effect.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: inhaled nitric oxide gas
What this could lead to: If it works, this could point toward a simple way to protect the heart, kidneys, and gut during surgery.
What could go wrong: This is a very small pilot study with only 40 people. It was not designed to prove the treatment works, only to see if it is worth studying further.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LAPAROSCOPIC ABDOMINAL SURGERIES

Contacts and locations

Locations

First Moscow State Medical University named after I.M. Sechenov (Sechenov University)

Moscow, 119048, Russia

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