New dialysis technique tested for better tolerance in kidney patients

NCT ID NCT01327391

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two types of dialysis in 415 older adults (ages 65-90) with chronic kidney failure: online hemodiafiltration and conventional hemodialysis. The goal was to see which method is better tolerated and whether it reduces heart problems and other complications. Patients received three sessions per week for 3-4 hours each. The trial is complete and focused on treatment side effects, quality of life, and cardiovascular outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
online hemodiafiltration (a blood-filtering procedure)
What this could lead to
If online hemodiafiltration proves better tolerated, it could become a preferred dialysis method for older patients with kidney failure, potentially reducing side effects during treatment.
What could go wrong
This is a completed phase 4 trial, so results are already known. The intervention is a variation of standard dialysis, not a breakthrough. Benefits may be modest and not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire

    Montpellier, 34295, France

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