10-Year medical mystery: tracking how stiff blood vessels harm the body

NCT ID NCT02840448

First seen Sep 30, 2025 · Last updated Apr 22, 2026 · Updated 28 times

Summary

This study aimed to understand how blood vessel stiffness in people with Williams Syndrome and related conditions affects organs like the heart, brain, and kidneys over time. Researchers followed 159 participants, including healthy volunteers, for up to 10 years with yearly check-ups and imaging tests. The goal was to gather knowledge about the long-term health impacts of these vascular differences, not to test a treatment.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • Washington University School of medicine

    St Louis, Missouri, 63110-1093, United States

Conditions

Explore the condition pages connected to this study.