Earlobe crease may reveal hidden heart danger in smokers

NCT ID NCT07427745

First seen Feb 25, 2026 · Last updated May 13, 2026 · Updated 8 times

Summary

This study looked at 404 adults aged 40-59 to see if a diagonal crease on the earlobe (Frank's sign) is linked to smoking and heart disease risk. Researchers compared smokers, former smokers, and non-smokers to find out if the crease appears more often in people who smoke. The goal is to help doctors quickly spot people who may have hidden heart risks just by looking at their ear.

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Contacts and locations

Locations

  • Samsun University Training and Research Hospital (Samsun City Hospital)

    Samsun, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.